Abraham L Sonenshein, PhD


Professor Emeritus of Molecular Biology & Microbiology



AB, Biochemical Sciences, Princeton University
PhD, Biology, MIT
Postdoctoral Training, Université de Paris XI


Campus: Boston
Office: Jaharis 411
Laboratory: Jaharis 425

Contact Information

Office Phone: 617-636-6761
Lab Phone: 617-636-6762
E-mail   Send an e-mail


Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Molecular Microbiology


Research Synopsis

I maintain an active research lab but no longer accept graduate students.

Our lab studies the regulation of gene transcription in spore-forming bacteria (Bacillus subtilis and Clostridium difficile) and related Gram-positive bacteria. The key questions under investigation are the nutritional signals that the cell senses as an indication that it must move from active growth to differentiation and the molecular mechanisms by which these signals are used to control expression of specific stationary phase, sporulation and virulence genes. The potential roles of transcription factors and the spores themselves as virulence factors are being investigated for the case of antibiotic-associated colitis caused by C. difficile. Although I no longer accept new students for thesis research in my lab, I continue to serve on thesis advisory committees and invite first-year students to pursue rotation projects in my lab.


Lab Members

Boris Belitsky, Research Assistant Professor Send an e-mail  Lab Research Page
Rajesh Biswas, Postdoctoral Scholar  Send an e-mail  Lab Research Page
William Newton, Research Technician  Send an e-mail  Lab Research Page
Tracy Washington, Postdoctoral Scholar  Send an e-mail Lab Research Page

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research