Abraham L Sonenshein, PhD

Abraham Sonenshein, PhD

Professor of Molecular Biology & Microbiology

 

Education

AB, Biochemical Sciences, Princeton University
PhD, Biology, MIT
Postdoctoral Training, Université de Paris XI

Location

Campus: Boston
Office: Jaharis 411
Laboratory: Jaharis 428

Contact Information

Office Phone: 617-636-6761
Lab Phone: 617-636-6762
E-mail   Send an e-mail

Links

Research Website  Lab Research Page
Recent Publications  Abstract in PubMed

Graduate Programs

Molecular Microbiology

 

Research Synopsis

Our lab studies the regulation of gene transcription in spore-forming bacteria (Bacillus subtilis and Clostridium difficile) and related Gram-positive bacteria. The key questions under investigation are the nutritional signals that the cell senses as an indication that it must move from active growth to differentiation and the molecular mechanisms by which these signals are used to control expression of specific stationary phase, sporulation and virulence genes. The potential roles of transcription factors and the spores themselves as virulence factors are being investigated for the case of antibiotic-associated colitis caused by C. difficile. Although I no longer accept new students for thesis research in my lab, I continue to serve on thesis advisory committees, direct the graduate course in microbial physiology (MBM207) and invite first-year students to pursue rotation projects in my lab. In addition, I have a very active postdoctoral training program.

 

Lab Members

Boris Belitsky, Research Assistant Professor Send an e-mail  Lab Research Page
Laurent Bouillaut, Research Associate Send an e-mail  Lab Research Page
Nadine Daou, Postdoctoral Scholar Send an e-mail Lab Research Page

Application for 2014 Admission

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