BA, MS, Biological Studies
University of Texas - Arlington
PhD, Endocrinology & Reproductive Physiology
University of Wisconsin - Madison
My work has been mainly involved in proliferating human embryonic stem cells (hESCs), deriving human induced pluripotent stem cells (iPSCs) and differentiating them toward lineages such as trophoblast and mesenchymal cells using various extracellular matrix proteins and small molecules. For example, I have used hESCs as a model for trophoblast differentiation to study the effects of cell-cell and cell-matrix interactions in two-dimensional (2D) and three-dimensional (3D) in vitro cell culture systems and successfully demonstrate the directed differentiation of hESCs to steriodogenic endocrine cells. My current research aims are to derive iPSCs and implement stem cell biology and bioengineering approaches in a 3D in vitro model for skin, retinal pigmented epithelium (RPE) and for study of tooth repair and regeneration.
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