Arthur Blum

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Arthur Blum 
Research Associate
Joel Weinstock, MD, Adviser

 

 

 

 

We are studying how cytokines regulate substance P receptor expression in inflammation like that seen in schistosomiasis and inflammatory bowel disease. We have an  Alexa-labelled substance  P that can be use to identify and isolate lymphocytes expressing the substance P receptor. We also have substance P receptor- transfected cell lines that express this receptor. We use these cell lines to measure the effect of certain cytokines on the binding, internalization and cycling of the receptor using confocal microscopy  

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