Megan Touchette


Megan Touchette
BS, Chemistry
Clarkson University
Potsdam, NY
PhD, Chemistry (Chemical Biology)
Stony Brook University
Stony Brook, NY
Postdoctoral Scholar
Aimee Shen, PhD, Adviser



Spore formation is critically important to C. difficile pathogenesis, as spores mediate disease transmission and recurrence; therefore, inhibiting spore assembly could prevent transmission. However, identifying coat assembly inhibitors requires a more mechanistic understanding of how C. difficile coat proteins interact and regulate coat assembly. The clostridial proteins SpoIVA and SipL have been shown to physically interact and are required for spore formation and proper spore coat localization. My project primarily focuses on elucidating the requirements for SpoIVA-SipL binding as well as determining the biological significance of this interaction.

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research