Laverne Melon

laverne

Laverne Melon
BA, Neuroscience
Middlebury  College
Middlebury, VT
MS, Behavioral Neuroscience
Binghamton University
Binghamton, NY
PhD, Addiction Neuroscience
Indiana University - Purdue University - Indianapolis
Postdoctoral Fellow  
Jamie Maguire, PhD, Adviser

 

Stress can disrupt the brain's homeostatic balance of inhibitory and excitatory regulation. The Maguire lab is working to understand the role that dysregulation of the GABA receptor system-the brain's major inhibitory neurotransmitter system-plays in the development and expression of various pathologies. As a member of Dr. Maguire's research team, I am investigating the mechanisms underlying the effects of stress on reproductive health. Processes such as ovulation and pubertal onset are regulated by hormones whose synthesis and release are under tight inhibitory control. We hypothesize that stress hormones can disrupt the normal tonic inhibition of reproductive hormones at the level of the hypothalamus, to instigate a host of negative effects on reproduction. I am also interested in understanding how the body takes advantage of this interaction of stress and reproductive hormones to increase stress resilience during times like mid-to late pregnancy. The ultimate goal of this work is to identify potential pharmacological targets to improve the prognosis of various stress-related pathologies.

As part of the TEACRS Program, I am teaching a new course on brain-based sex differences this fall in the Honors College at UMass - Boston

Back to the Maguire Profile Page

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research