Anne McCabe

anne

AB, Molecular & Cellular Biology
Harvard University
Cambridge, MA
MS, PhD, Molecular Biology
Princeton University
Princeton, NJ
Postdoctoral Scholar
Joan Mecsas, PhD, Adviser

 

 

 

My research is focused on two Gram-negative pathogens, Yersinia pseudotuberculosis and Klebsiella pneumoniae. I am studying how Yersinia regulates translocation of bacterial effector proteins into host cells during infection to interfere with host immune responses. Translocation of bacterial effectors into the host cells via the Type III secretion machinery occurs after cell contact, but the mechanism of sensing cell-contact and regulation of translocation remains unknown. Additionally, I am interested in how Klebsiella develops resistance to a metabolic inhibitor, and whether this can be used to treat MDR infections.

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research