Roaya Alqurashi

Roaya Alqurashi
Pharm D, Pharmacy
King Abdulaziz University
Jeddah, Saudi Arabia
Pharm D, Pharmacy
Massachusetts College of Pharmacy
Boston, MA
PhD Student in Pharmacology & Experimental Therapeutics
Amy Yee, PhD, Adviser

 

 

 

Epilepsy is one of the most common chronic neurological disorders, affecting 1% of the population world-wide. Despite advances in pharmacological and surgical methods of reducing seizures in epilepsy, the mechanisms that cause epilepsy remain poorly understood and there are no definitive treatments. For example, 30% of patients with epilepsy have uncontrolled seizures, despite multiple pharmacological interventions. Thus, understanding molecular mechanisms mediating epileptogenesis is critical for developing more effective therapies for epilepsy. The Yee lab has identified a correlation between epileptogenesis and Wnt signaling. My thesis is analyzing a genetic model of Wnt-signaling-induced epilepsy with correlates in human disease. We are examining a combinational drug therapy that both crosses the blood-brain barrier and suppresses Wnt signaling as an intervention in the epileptogenic process.

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research