Mona Bawazeer

Mona Bawazeer
Pharm D, Pharmacy
King Abdulaziz University
Jeddah, Saudi Arabia
MS, Pharmaceutical Sciences
Albany College of Pharmacy
Albany, NY
PhD Student in Pharmacology & Experimental Therapuetics
Theoharis Theoharides, MD, PhD, Adviser

 

 

Psoriasis (Ps) is characterized by keratinocyte proliferation and chronic inflammation driven primarily by high TNF and IL-17. Ps plaques contain increased number of mast cells (MCs), which contribute to Ps and other inflammatory disorders. It was thought that IL-17 derives from T-cells, but recent evidence indicates that MCs are the only cells expressing IL-17 in rheumatoid arthritis joints and in psoriatic skin. Therefore, I am investigating the ability of various cytokines and neuropepties to stimulate MC release of IL-17 and how this can be inhibited..

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