Michaela Tolman


Michaela Tolman
BA, Neuroscience & Behavior
Wesleyan University
Middletown, CT
Neuroscience PhD Student
Philip Haydon, PhD, Adviser




Over 5 million people in the United States have Alzheimer’s Disease (AD). There is currently neither a cure or a complete understanding of the mechanisms at the onset of this disease. We know that some of the first cells to die are part of the cholinergic system. In order to better understand the role of cholinergic inputs on cognition and behavior, I am investigating the effect of acetylcholine signaling on astrocytes, the most numerous cell type in the brain. Using high performance liquid chromatography, in vivo microdialysis, optogenetics, and cell type specific knock-outs in mice, I will determine what role acetylcholine plays in regulating cognitive homeostasis through astrocyte release of gliotransmitters.

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research