Michael Pereira


Michael Pereira
BS, MS, Microbiology
University of Rhode Island
Kingston, RI
PhD Student in Molecular Microbiology
John Leong, MD, PhD, Adviser




Enterohemorrhagic Escherichia coli (EHEC) is a human intestinal pathogen that has the ability to cause widespread outbreaks in developed countries. Since EHEC is unable to colonize the conventional mouse intestine, our laboratory has engineered the mouse pathogen Citrobacter rodentium as a model for EHEC infection. My research involves the identification of factors that enable murine intestinal colonization by Citrobacter rodentium, focusing on the expression of Type IV pilus genes. By expressing these “mouse-specific” factors in EHEC, we hope to generate an EHEC strain that can be used in a more accurate in vivo infection model.

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February 15: Building Diversity in Biomedical Sciences

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