MD, PhD Student in Genetics
Rajendra Kumar-Singh, PhD, Adviser
Age-related macular degeneration (AMD) is the leading cause of vision loss in people age 65 and older in the United States and it is hypothesized that the over activation or loss of regulatory control of the alternative pathway of the complement system plays a significant role in the pathogenesis of AMD. As a negative regulator of membrane attack complex (MAC) deposition, CD59 is a particularly promising candidate to limit over-activation of the alternative pathway and resulting damage. My thesis research examined this possibility using mouse models.
I am now completing the fourth year of medical school.