2012

Ezeokonkwo C, Ghazy MA, Zhelkovsky A, Yeh P-C, Moore, C. Novel interactions at the essential N-terminus of poly(A) polymerase that could regulate poly(A) addition in Saccharomyces cerevisiae. FEBS Lett. 586: 1173-1179.

Foley CJ, Luo C, O’Callaghan K, Hinds P, Covic L, Kuliopulos A. 2012. Matrix metalloprotease-1a promotes tumorigenesis and metastasis. J Biol Chem. in press. 

O'Connell DP, LeBlanc DF, Cromley D, Billheimer J, Rader DJ, Bachovchin WW. 2012. Design and synthesis of boronic acid inhibitors of endothelial lipase. Bioorg Med Chem Lett. 22: 1397-1401.

Pritchard S, Bianchi DW. 2012. Fetal cell microchimerism in the maternal heart: baby gives back. Circ. Res. 110: 3-5.

2011

Binder C, Cashman SM, Read SP, Kumar-Singh R. 2011. Nuclear targeted delivery of macromolecules to retina and cornea. J Gene Med. 12: 158-170.

Bradley ES, Bodi K, Ismail AM, Camilli A. 2011. A genome-wide approach to discovery of small RNAs involved in regulation of virulence in Vibrio cholerae. PLoS Pathog. 7: e1002126.

Chan WW, Wise SC, Kaufman MD, Ahn Y-M, Ensinger CL, Haack T, Hood MM, Jones J, Lord JW, Lu WP, Miller D, Patt WC, Smith BD, Petillo PA, Rutkoski TJ, Telikepalli H, Vogeti L, Yao T, Abendroth J, Chun L, Clark R, Evangelista P, Gavrilescu LC, Lazarides K, Zaleskas VM, Stewart L, Van Etten RA, Flynn DL. 2011. Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036. Cancer Cell 19: 556-568.  

Cisowski J, O’Callaghan K, Kuliopulos A, Yang J, Nguyen N, Deng Q, Yang E , Fogel M, Tressel S, Foley C, Agarwal A, Hunt III SW, McMurry T, Brinckerhoff L, Covic L. Targeting protease-activated receptor-1 with cell-penetrating pepducins in lung cancer. Amer J Pathol, 179: 513-523.

Enloe BM, Jay DG. 2011. Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity. J Neurooncol. 102: 225-35. 

Ezeokonkwo C, Zhelkovsky A, Lee R, Bohm A, Moore CL. 2011. A flexible linker region in Fip1 is needed for efficient mRNA polyadenylation. RNA 17: 652-664.

Keller PJ, Arendt LM, Skibinski A, Logvinenko T, Klebba I, Dong S, Smith AE, Prat A, Perou CM, Gilmore H, Schnitt S, Naber SP, Garlick JA, Kuperwasser C. 2011. Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci USA Epub ahead of print. 

Krolewski RC, Jang W, Schwob JE. 2011. The generation of olfactory epithelial neurospheres in vitro predicts engraftment capacity following transplantation in vivo. Exp Neurol. 229: 308-323. 

Numata K, Reagan MR, Goldstein RH, Rosenblatt M, Kaplan DL. 2011. Spider silk-based gene carriers for tumor cell-specific delivery. Bioconjug Chem. 22: 1605-1610.

Packard A*, Schnittke N*, Romano R, Sinha S, Schwob JE 2011. ΔNp63 regulates stem cell dynamics in the mammalian olfactory epithelium. J Neurosci. 31: 8748-8759.*equal contribution

Pritchard S, Hoffman AM, Johnson KL, Bianchi DW. 2011. Pregnancy-associated progenitor cells: An under-recognized potential source of stem cells in maternal lung. Placenta 32: S298-S303.  

Scepansky E, Goldstein R, Rosenblatt M. 2011. Preclinical orthotopic and intracardiac injection models of human breast cancer metastasis to bone and their use in drug discovery. Curr Protoc Pharmacol. Chapter 14, Unit 14.18.

Sevigny LM, Austin KM, Zhang P, Kasuda S, Koukos G, Sharifi S, Covic L, Kuliopulos A. 2011. Protease-activated receptor-2 modulates protease-activated receptor-1-driven neointimal hyperplasia. Arterioscler Thromb Vasc Biol. 31: e100-106.

Smith PM, Jacque B, Conner JR, Poltorak A, Stadecker MJ. 2011. IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection. PLoS Pathog. 7: e1002272. 

Tressel SL, Kaneider NC, Kasuda S, Foley C, Koukos G, Austin K, Agarwal A, Covic L, Opal SM, Kuliopulos A. 2011. A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis. EMBO Mol Medicine 3: 370-384.

Wang YZ, Yamagami T, Gan Q, Wang Y, Zhao T, Hamad S, Lott P, Schnittke N, Schwob JE, Zhou CJ. 2011. Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration. J Cell Sci.124: 1553-1563.

Weinkauf C, Salvador R, Pereiraperrin M. 2011. Neurotrophin receptor TrkC is an entry receptor for Trypanosoma cruzi in neural, glial, and epithelial cells. Infect Immun. 79: 4081-4087.

2010

Conner JR, Smirnova II, Moseman AP, Poltorak A. IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-κB p50. Proc Natl Acad Sci USA 107: 11477-11482.

Goldstein RH, Weinberg RA, Rosenblatt M. 2010. Of mice and (wo)men: mouse models of breast cancer metastasis to bone. J Bone Miner Res. 25: 431-436.

Goldstein RH, Reagan MR, Anderson K, Kaplan DL, Rosenblatt M. 2010. Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res. 70: 10044-10050.

Guo Z, Packard A, Krolewski RC, Harris MT, Manglapus GL, Schwob JE. 2010. J Comp Neurol. 51: 4395-4418.

Johnson LN, Cashman SM, Read SP, Kumar-Singh R. 2009. Cell penetrating peptide POD mediates delivery of recombinant proteins to retina, cornea and skin. Vision Res 50: 686-697.

Rasetti R, Mattay VS, Stankevich B, Skjei K, Blasi G, Sambataro F, Arrillaga-Romany IC, Goldberg TE, Callicott JH, Apud JA, Weinberger DR. 2010. Modulatory effects of modafinil on neural circuits regulating emotion and cognition. Neuropsychopharmacology 35: 2101-2109.

Read SP, Cashman SM, Kumar-Singh R. 2010. POD nanoparticles expressing GDNF provide structural and functional rescue of light-induced retinal degeneration in an adult mouse. Mol Ther. 18: 1917-1926.

Read SP, Cashman SM, Kumar-Singh R. 2010. A poly(ethylene) glycolylated peptide for ocular delivery compacts DNA into nanoparticles for gene delivery to post-mitotic tissues in vivo. J Gene Med. 12: 86-96.

Russo JW, Castellot JJ. 2010. CCN5: biology and pathophysiology. J Cell Commun Signal 4: 119-130.

Rosenbach A, Dignard D, Pierce JV, Whiteway M, Kumamoto CA. 2010. Adaptations of Candida albicans for growth In the mammalian intestinal tract. Eukaryot Cell 9: 1075-1086.  

Stampfer SD, Lou H, Cohen GH, Eisenberg RJ, Heldwein EE. Structural basis of local, pH-dependent conformational changes in glycoprotein B from Herpes Simplex virus 1. J Virol 84: 12924-12933.

Swift S, Xu J, Trivedi V, Austin KM, Tressel SL, Zhang L, Covic L, Kuliopulos A. 2010. A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization. J Biol Chem. 285: 11402-11410.

Wozniak RA, Waldor MK. 2010. Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow. Nat Rev Microbiol. 8: 522-563. 

2009

Conner JR, Smirnova II, Poltorak, A.2009. A mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived mice. J. Exp. Med. 206:1615-1631.

Liu S, Goldstein RH, Scepansky EM, Rosenblatt M. 2009. Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone. Cancer Res. 69: 8742-8751.

Nelson EJ, Harris JB, Morris JG Jr, Calderwood SB, Camilli A. 2009. Cholera transmission: the host, pathogen and bacteriophage dynamic.  Nat Rev Microbiol. 7:693-702.

Nelson EJ, Tanudra A, Chowdhury A, Kane AV, Qadri F, Calderwood SB, Coburn J, Camilli A. 2009. High prevalence of spirochetosis in cholera patients, Bangladesh. Emerg Infect Dis. 15: 571-573.

Schild S, Nelson EJ, Bishop AL, Camilli A. 2009. Characterization of Vibrio cholerae outer membrane vesicles as a candidate vaccine for cholera. Infect Immun. 77: 472-484.

Wei L, McKeon F, Russo JW, Lemire J, Castellot J. 2009. Domain-and species-specific monoclonal antibodies recognize the Von Willebrand Factor-C domain of CCN5. J Cell Commun Signal. 3: 65-77.

Weinkauf C, PereiraPerrin M. 2009. Trypanosoma cruzi promotes neuronal and glial cell survival through the neurotrophic receptor TrkC. Inf. Immun. 77: 1368-1375.

Wozniak, RA, Waldor, MK. 2009. A toxin-antitoxin system promotes the maintenance of an integrative conjugative element. PLoS Genet 5: e1000439.

Wozniak, RA, Waldor, MK. 2009. Comparative ICE genomics: insights into the evolution of the SXT/R391 family of ICEs. PLoS Genet 5: e1000786.

Yang E, Boire A, Agarwal A, Nguyen N, O'Callaghan K, Tu P, Kuliopulos A, Covic L. 2009. Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res 69: 6223-6231.

2008

Conner JR, Smirnova II, Poltorak A. 2008. Forward genetic analysis of toll-like receptor responses in wild-derived mice reveals a novel anti-inflammatory role for IRAK1BP1. J. Exp. Med. 205: 305-314.

Hao Y, Wong R, Feig LA. 2008. RalGDS couples growth factor signaling to Akt activation. Mol Cell Biol. 28: 2851-2859.

Martinez-Wilson HF, Tamayo R, Tischler AD, Lazinski DW, Camilli A. 2008. The Vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering the cyclic diguanylate level. J. Bacteriol. 190: 6439-6447. 

Meinke G, Ezeokokwo C, Balbo P, Moore C, Bohm A. 2008. Structure of yeast poly(A) polymerase in complex with the polymerase-binding domain of Fip1. Biochemistry 47: 6859-6869. 

Nelson EJ, Chowdhury A, Flynn J, Schild S, Bourassa L, Shao Y, LaRocque RC, Calderwood SB, Qadri F, Camilli A. 2008. Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the aquatic environment. PLoS Pathog 4: e1000187.

Osorio CR, Marrero J, Wozniak RA, Lemos ML, Burrus V, Waldor MK. 2008. Genomic and functional analysis of ICEPdaSpa1, a fish-pathogen-derived SXT-related integrating conjugative element that can mobilize a virulence plasmid. J. Bacteriol. 190: 3353-3361.

Schild S, Nelson EJ, Camilli A. 2008. Immunization with Vibrio cholerae outer membrane vesicles induces protective immunity in mice. Infect Immun. 76: 4554-4563.