Student Publications

2012


Foley CJ, Luo C, O’Callaghan K, Hinds P, Covic L, Kuliopulos A. 2012. Matrix metalloprotease-1a promotes tumorigenesis and metastasis. J Biol Chem. in press. 

Gündüz V, Kong E, Bryan CD, Hinds PW. 2012. Loss of the retinoblastoma tumor suppressor protein in murine calvaria facilitates immortalization of osteoblast-adipocyte bipotent progenitor cells characterized by low expression of N cadherin.Mol Cell Biol. in press.

Pritchard S, Bianchi DW. 2012. Fetal cell microchimerism in the maternal heart: baby gives back. Circ Res. 110: 3-5. books

2011


Binder, C, Cashman, SM, Read, SP, Kumar-Singh, R. 2011. Nuclear targeted delivery of macromolecules to retina and cornea. J Gene Med. 13: 158-170. books

Cingöz O, Coffin, JM. 2011. Endogenous murine leukemia viruses: Relationship to XMRV and related sequences detected in human DNA samples. Adv Virol. Epub ahead of print. books

Cingöz O, Paprotka T, Delviks-Frankenberry KA, Wildt S, Hu WS, Pathak VK, Coffin JM. 2011. Characterization, mapping and distribution of the two XMRV parental proviruses. J Virol. 86: 328-338. books

Cisowski J, O’Callaghan K, Kuliopulos A, Yang J, Nguyen N, Deng Q, Yang E, Fogel M, Tressel S, Foley C, Agarwal A, Hunt III SW, McMurry T, Brinckerhoff L, Covic L. Targeting protease-activated receptor-1 with cell-penetrating pepducins in lung cancer. Amer J Pathol.  179: 513-523. books

Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, Lander ES. 2011. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 146: 633-644. books

Koukos G, Sevigny L, Zhang P, Covic L, Kuliopulos A. 2011. Serine and metalloprotease signaling through PAR1 in arterial thrombosis and vascular injury. IUBMB Life 63: 412-418. books

Paprotka T*, Delviks-Frankenberry KA*, Cingöz O*, Martinez A, Kung H-J, Tepper CG, Hu W-S, Fivash MJ, Jr, Coffin JM, Pathak VP. 2011. Recombinant origin of the retrovirus XMRV. Science 333: 97-101 * equal contribution. books

Pritchard S, Hoffman AM, Johnson KL, Bianchi DW. 2011. Pregnancy-associated progenitor cells: an under-recognized potential source of stem cells in maternal lung. Placenta 32: S298-303. books

Richardson K, Lai CQ, Parnell LD, Lee YC, Ordovas JM. 2011. A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. BMC Genomics 12: 504. books

Richardson K, Louie-Gao Q, Arnett DK, Parnell LD, Lai C-Q, Davalos A, Fox CS, Demissie S, Cupples LA, Fernandez-Hernando C, Ordovas JM. 2011. The PLIN4 variant rs8887 modulates obesity Rrelated phenotypes in humans through creation of a novel miR-522 seed site. PLoS One 6: e17944. books

Sevigny LM, Austin KM, Zhang P, Kasuda S, Koukos G, Sharifi S, Covic L, Kuliopulos A. 2011. Protease-activated receptor-2 modulates protease-activated receptor-1-driven neointimal hyperplasia. Arterioscler Thromb Vasc Biol. 31: e100-106. books

Sevigny LM, Zhang P, Bohm A, Lazarides K, Perides G, Covic L, Kuliopulos A. 2011. Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins. 108: 8491-8496. books

Tressel SL, Kaneider NC, Kasuda S, Foley C, Koukos G, Austin K, Agarwal A, Covic L, Opal SM, Kuliopulos A. 2011. A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis. EMBO Mol Med. 3: 370-384. books

 

2010


Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C. 2010. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc Natl Acad Sci USA 107: 21737-21742. books

Greenwald DL, Cashman S, Kumar-Singh R. 2010. Engineered zinc-finger nuclease mediated homologous recombination of the human rhodopsin gene. Invest Ophthalmol Vis Sci. 51: 6374-6380. books

Oakes B, Tai AK, Cingöz O, Henefield MH, Levine S, Coffin JM, Huber BT. 2010. Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequences. Retrovirology 7: 109. books

Read SP, Cashman SM, Kumar-Singh R. 2010. POD nanoparticles expressing GDNF provide structural and functional rescue of light-induced retinal degeneration in an adult mouse. Mol Ther. 18: 1917-1926. books

Read SP, Cashman SM, Kumar-Singh R. 2010. A poly(ethylene) glycolylated peptide for ocular delivery compacts DNA into nanoparticles for gene delivery to post-mitotic tissues in vivo. J Gene Med. 12: 86-96. books

Robinson MJ, Erlwein OW, Kaye S, Weber J, Cingöz O, Patel A, Walker MM, Kim WJ, Uiprasertkul M, Coffin JM, McClure MO. 2010. Mouse DNA contamination in human tissue tested for XMRV. Retrovirology 7: 108. books

Rosenbach A, Dignard D, Pierce JV, Whiteway M, Kumamoto CA. 2010. Adaptations of Candida albicans for growth in the mammalian intestinal tract. Eukaryot Cell 9: 1075-1086.  books

Sosa-García B, Gunduz V, Vázquez-Rivera V, Cress WD, Wright G, Bian H, Hinds PW, Santiago-Cardona PG. 2010. A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation. PLoS One 5: e13954. books

Swift S, Xu J, Trivedi V, Austin KM, Tressel SL, Zhang L, Covic L, Kuliopulos A. 2010. A novel protease-activated receptor-1 interactor, Bicaudal D1, regulates G protein signaling and internalization. J Biol Chem. 285: 11402-11410. books

2009


Heidtman M, Chen EJ, Moy MY, Isberg RR. 2009. Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways. Cell Microbiol. 11: 230-248. books

Hu MG, Deshpande A, Enos M, Mao D, Hinds EA, Hu GF, Chang R, Guo Z, Dose M, Mao C, Tsichlis PN, Gounari F, Hinds PW. 2009. A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis. Cancer Res. 69: 810-818. books

Hsiao FC, Tai AK, Deglon A, Sutkowski N, Longnecker R, Huber BT. 2009. EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM. Virology 385: 261-266. books

Johnson LN, Cashman SM, Read SP, Kumar-Singh R. 2009. Cell penetrating peptide POD mediates delivery of recombinant proteins to retina, cornea and skin. Vision Res. epub ahead of print. books

Junyent M, Tucker KL, Smith CE, Lane JM, Mattei J, Lai CQ, Parnell LD, Ordovas JM. 2009. The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican Health Study. Nutr Metab Cardiovasc Dis. epub ahead of print. books

Lazebnik MB, Tussie-Luna MI, Hinds PW, Roy AL. 2009. Williams-Beuren syndrome-associated transcription factor TFII-I regulates osteogenic marker genes. J Biol Chem. 284: 36234-236239. books

Ramos B, Valín A, Sun X, Gill G. 2009. Sp4-dependent repression of neurotrophin-3 limits dendritic branching. Mol Cell Neurosci. 42: 152-159. books

Richardson K, Ordovas JM. 2009. Functional genomic and epidemiological studies reveal novel genes regulating cholesterol metabolism. Gene Med. 27: 96. books

2008


Al-Fulaij MA, Ren Y, Beinborn M, Kopin AS. 2008. Pharmacological analysis of human D1 AND D2 dopamine receptor missense variants. J Mol Neurosci. 34: 211-223. books

Agarwal A, Covic L, Sevigny LM, Kaneider NC, Lazarides K, Azabdaftari G, Sharifi S, Kuliopulos A. 2008. Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer. Mol Cancer Ther. 7: 2746-2757. books

Fillmore CM, Kuperwasser C. 2008. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res. 10: R25. books

Gutierrez GM, Kong E, Sabbagh Y, Brown NE, Lee JS, Demay MB, Thomas DM, Hinds PW. 2008. Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proc Natl Acad Sci USA 105: 18402-18407. books

Lazebnik MB, Tussie-Luna MI, Roy AL. 2008. Determination and functional analysis of the consensus binding site for TFII-I family member BEN, implicated in Williams-Beuren syndrome. J Biol CHem. 283: 11078-11082. books

Sims HI, Baughman CB, Schnitzler GR. 2008. Human SWI/SNF directs sequence-specific chromatin changes on promoter polynucleosomes. Nucleic Acids Res. 36: 6118-6131. books

Whalen KA, Weber GF, Benjamin TL, Schaffhausen BS. 2008. Polyomavirus middle T antigen induces the transcription of osteopontin, a gene important for the migration of transformed cells. J Virol. 82: 4946-4954. books

Zimmerman RS, Rosenberg N. 2008. Changes in p19Arf localization accompany apoptotic crisis during pre-B-cell transformation by Abelson murine leukemia virus. J Virol. 82: 8383-8391. books

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