Recent Publications from the Thorpe Lab

Research Publications Immunology

 

Jandhyala DM, Thorpe CM, Magun B.  2012. Ricin and shiga toxins: effects on host cell signal transduction. Curr Top Microbiol Immunol. 357: 41-65. books

Wang H, Paton JC, Thorpe CM, Bonder CS, Sun WY, Paton AW. 2010. Tissue factor–dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by shiga toxigenic Escherichia coli. J Infect Dis. 202: 1415-1423. books

Jandhyala DM, Rogers TJ, Kane A, Paton AW, Paton JC, Thorpe CM. 2010. Shiga toxin 2 and flagellin from Shiga toxigenic Escherichia coli super-induce IL-8 through synergistic effects on host SAPKinase activation. Infect Immun. 78: 2984-2894. books

Rajendran P, Rajan DP, Kang G, Thorpe CM. 2009. Shiga toxin-producing Escherichia coli infection in South India. J Med Microbiol. 58:1525-1526.  books

Wolfson JJ, Jandhyala DM, Gorczyca LA, Qadeer Z, Thorpe CM, Manning SD, Hadler J, Rudrik JT. 2009. Prevalence of the operon encoding subtilase cytotoxin in non-O157 shiga toxin-producing Escherichia coli isolated from humans in the United States. J Clin Microbiol 47: 3058-3059. books

Wolfson JJ, May KL, Thorpe CM, Jandhyala DM, Paton JC, Paton AW. 2008. Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways. Cell Microbiol 10: 1775-1786. books

Jandhyala DM, Ahluwalia A, Obrig T,Thorpe CM. 2008. ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression. Cell Microbiol 10: 1468-1477. books

Chong DC, Paton JC, Thorpe CM, Paton AW. 2008. Clathrin-dependent trafficking of subtilase cytotoxin, a novel AB5 toxin that targets the endoplasmic reticulum chaperone BiP. Cell Microbiol 10: 795-806. books

Khaitan A, Jandhyala DM, Thorpe CM, Ritchie JM, Paton AW. 2007. The operon encoding SubAB, a novel cytotoxin, is present in shiga toxin-producing Escherichia coli isolates from the United States. J Clin Microbiol 45: 1374-1375. books

Johnson KE, Thorpe CM, Sears CL. 2006. The emerging clinical importance of non-O157 Shiga toxin-producing Escherichia coli. Clin Infect Dis 43: 1587-1595. books

Paton AW, Beddoe T, Thorpe CM, Whisstock JC, Wilce MC, Rossjohn J, Talbot UM, Paton JC. 2006. AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature 443: 548-552. books

Colpoys WE, Cochran BH, Carducci TM, Thorpe CM. 2005. Shiga toxins activate translational regulation pathways in intestinal epithelial cells. Cell Signal 17: 891-899. books

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