Recent Publications from the Selsing Lab

Research Publications Genetics Immunology

 

Shansab M, Eccleston JM, Selsing E. 2011. Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region. Eur J Immunol. Epub ahead of print. books

Shansab M, Selsing E. 2011. p21 is dispensable for AID-mediated class switch recombination and mutagenesis of immunoglobulin genes during somatic hypermutation. Mol Immunol. 186: 973-978. books

Eccleston J, Schrader CE, Yuan K, Stavnezer J, Selsing E. 2009. Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats. J Immunol 183: 1222-1228. books

Wuerffel R, Wang L, Grigera F, Manis J, Selsing E, Perlot T, Alt FW, Cogne M, Pinaud E, Kenter AL. 2007. S-S synapsis during class switch recombination is promoted by distantly located transcriptional wlements and activation-induced deaminase. Immunity 27: 711-722. books

Schrader CE, Guikema JE, Linehan EK, Selsing E, Stavnezer J. 2007. Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. J Immunol 179: 6064-6071. books

Han JH, Akira S, Calame K, Beutler B, Selsing E, Imanishi-Kari T. 2007. Class switch recombination and somatic hypermutation in early mouse B Cells are mediated by B Cell and toll-like receptors. Immunity 27: 64-75. books

Huang FT, Yu K, Balter BB, Selsing E, Oruc Z, Khamlichi AA, Hsieh CL, Lieber MR. 2007. Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Sμ class switch region. Mol Cell Biol 27: 5921-5932. books

Selsing E. 2006. Ig class switching: targeting the recombinational mechanism. Curr Opin Immunol 18: 249-254. books

D'Avirro N, Truong D, Xu B, Selsing E. 2005. Sequence transfers between variable regions in a mouse antibody transgene can occur by gene conversion. J Immunol 175: 8133-8137. books

Min IM, Selsing E, 2005. Antibody class switch recombination: roles for switch sequences and mismatch repair proteins. Adv Immunol 87: 297-328. books

Min IM, Rothlein LR, Schrader CE, Stavnezer J, Selsing E. 2005. Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2. J Exp Med 201: 1885-1890. books

Min IM, Schrader CE, Vardo J, Luby, TM, D'Avirro N, Stavnezer J, Selsing E. 2003. The sμ tandem repeat region is critical for Ig isotype switching in the absence of msh2. Immunity 19: 515-524. books

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