The Graduate Program in Cellular and Molecular Physiology (CMP) is strongly committed to educating outstanding scientists and physician-scientists who will pursue biomedical research careers in both academic settings and in the biotech/pharmaceutical industry. Our program’s focus is on basic biological processes and their relationship to the molecular and cellular basis of human disease. We provide opportunities for dissecting the pathways governing disease processes.
Students who join the CMP Program are trained by a diverse and active group of faculty members from the Molecular Physiology & Pharmacology Department, as well as from Neuroscience, Medicine and the Cummings School of Veterinary Medicine. Our faculty members apply cellular and molecular biology, molecular genetics, bioengineering and genomics-based research to the central issues in human development and disease. We employ C. elegans and mouse models of development and disease and our labs are developing novel gene- and cell-based therapeutics that might someday be capable of prolonging life as well as correcting inborn errors of metabolism, chronic wound healing, cardiovascular disease, and cancer.
Our emphasis on human disease is highlighted by both the broad research interests of our faculty and our graduate student curriculum. All students in the CMP Program, in addition to coursework in the basic sciences, take our nationally recognized Pathobiology course, which combines clinical and pathology sessions with discussions of basic research in specific diseases.
The CMP Program is focused on three particular areas of strength. The first is study of molecular signaling networks controlling cell growth and motility. This area of research has implications for understanding the genetic basis of cancer, the mechanisms regulating wound healing, the molecular control of physiologic and pathologic angiogenesis, and the pathogenesis of pulmonary disease. A second strength is the molecular and cellular dissection of those protein- and lipid-based trafficking pathways that are likely to regulate breast cancer progression, liver disease, and neurodegenerative disorders. A third area of strength is the investigation of signaling within and among neurons and glia. These studies relate to spinal cord injury, motor disease, brain cancer, obesity, and neurodegenerative diseases associated with aging.
CMP Student Guide