Student Publications

2012


Demidova-Rice TN, Wolf L, Deckenback J, Hamblin MR, Herman IM. 2012. Human platelet-rich plasma- and extracellular matrix-derived peptides promote impaired cutaneous wound healing in vivo. PLoS One 7: e32146. Abstract in PubMed

Desrochers TM, Shamis Y, Alt-Holland A, Kudo Y, Takata T, Wang G, Jackson-Grusby L, Garlick JA. 2012. The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma. Epigenetics 7: 1. Abstract in PubMed 

Hewitt KJ, Shamis Y, Knight E, Smith A, Maione A, Alt-Holland A, Sheridan SD, Haggarty SJ, Garlick JA. 2012. PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation. J Cell Sci. Epub ahead of print. Abstract in PubMed

Shamis Y, Hewitt KJ, Bear SE, Alt-Holland A, Qari H, Margvelashvilli M, Knight EB, Smith A, Garlick JA. 2012. iPSC-derived fibroblasts demonstrate augmented production and assembly of extracellular matrix proteins. In Vitro Cell Dev Biol Anim. 48: 112-122. Abstract in PubMed

2011


Alt-Holland A, Sowalsky AG, Szwec-Levin Y, Shamis Y, Hatch H, Feig LA, Garlick JA. 2011. Suppression of E-Cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src. J Invest Dermatol. 131: 2306-2315. Abstract in PubMed

Carlson M, Faria K, Shamis Y, Leman J, Ronfard V, Garlick J. 2011. Epidermal stem cells are preserved during commercial scale manufacture of a bilayered, living cellular construct (Apligraf®). Tissue Eng Part A 17: 487-493. Abstract in PubMed

Demidova-Rice TN, Geevarghese A, Herman IM 2011. Bioactive peptides derived from vascular endothelial cell extracellular matrices promote microvascular morphogenesis and wound healing in vitro. Wound Repair Regen. 19: 59-70. Abstract in PubMed

Greenberg L, Hatini V. 2011. Systematic expression and loss-of-function analysis defines spatially restricted requirements for Drosophila RhoGEFs and RhoGAPs in leg morphogenesis. Mech Dev. 128: 5-17. books

Hoeing K, Zscheppang K, Mujahid S, Murray S, Volpe MV, Dammann CE, Nielsen HC. 2011. Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation. Biochim Biophys Acta 1813: 480-491. books

Hewitt KJ, Shamis Y, Hayman RB, Margvelashvili M, Dong S, Carlson MW, Garlick JA. 2011. Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells. PLoS One 6: e17128. books

Hoeing K, Zscheppang K, Mujahid S, Murray S, Volpe MV, Dammann CE, Nielsen HC. 2011. Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation. Biochim Biophys Acta 1813: 480-491. books

Keller PJ, Arendt LM, Skibinski A, Logvinenko T, Klebba I, Dong S, Smith AE, Prat A, Perou CM, Gilmore H, Schnitt S, Naber SP, Garlick JA, Kuperwasser C.  2011. Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci USA,  109: 2772-2777. books

Krause S, Jondeau-Cabaton A, Dhimolea E, Soto AM, Sonnenschein C, Maffini MV. 2011. A dual regulation of breast tubulogenesis by extracellular matrix composition and stromal cells. Tissue Eng Part A Epub ahead of print. books

Krolewski RC, Jang W, Schwob JE. 2011. The generation of olfactory epithelial neurospheres in vitro predicts engraftment capacity following transplantation in vivo. Exp Neurol. 229: 308-323. books

Markowska AI, Jefferies KC, Panjwani N. 2011. Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells. J Biol. Chem. 286: 29913-29921. books

Packard A, Giel-Moloney M, Leiter A, Schwob JE. 2011. Progenitor cell capacity of NeuroD1-expressing globose basal cells in the mouse olfactory epithelium. J Comp Neurol. 19: 3580-3596. books

Packard A*, Schnittke N*, Romano R, Sinha S, Schwob JE 2011. ΔNp63 regulates stem cell dynamics in the mammalian olfactory epithelium. J Neurosci. 31: 3748-8759  *equal contribution. books

Pageau SC, Sazonova OV, Wong JY, Soto AM, Sonnenschein C. 2011.  The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture. Biomaterials 32: 7169-7180. books

Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C. 2011. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell 8: 149-163.  Abstract in PubMed

Rudnick JA, Arendt LM, Klebba I, Hinds JW, Iyer V, Gupta PB, Naber SP, Kuperwasser C. 2011. Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. PLoS One 6: e24605. Abstract in PubMed

Shamis Y, Hewitt KJ, Carlson MW, Margvelashvilli M, Dong S, Kuo CK, Daheron L, Egles C, Garlick JA. Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents. Stem Cell Res Ther. 2: 10. books

Sowalsky AG, Alt-Holland A, Shamis Y, Garlick JA, Feig LA. 2011. RalA function in dermal fibroblasts is required for the progression of squamous cell carcinoma of the skin. Cancer Res. 71: 758-767. Abstract in PubMed

Sweigard JH, Cashman SM, Kumar-Singh R. 2011. Adenovirus-mediated delivery of CD46 attenuates the alternative complement pathway on RPE: implications for age-related macular degeneration. Gene Ther. 18: 613-621.  books

Wang YZ, Yamagami T, Gan Q, Wang Y, Zhao T, Hamad S, Lott P, Schnittke N, Schwob JE, Zhou CJ. 2011. Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration. J Cell Sci. 124: 1553-1563. books

2010


Arendt LM, Rudnick JA, Keller PJ, Kuperwasser C. 2010. Stroma in breast development and disease. Semin Cell Dev Biol. 21: 11-18.  Abstract in PubMed

Cairns DM, Uchimura T, Kwon H, Lee PG, Seufert CR, Matzkin E, Zeng L. 2010. Muscle cells enhance resistance to pro-inflammatory cytokine-induced cartilage destruction. Biochem Biophys Res Commun. 392: 22-28. Abstract in PubMed

Cairns DM, Lee PG, Uchimura T, Seufert CR, Kwon H, Zeng L. 2010. The role of muscle cells in regulating cartilage matrix production. J Orthop Res. 28: 529-536. Abstract in PubMed

Egles C, Garlick JA, Shamis Y. 2010.  Three-dimensional human tissue models of wounded skin. Methods Mol Biol. 585: 345-359.  books

Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C. 2010. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc Natl Acad Sci USA 107: 21737-21742. books

Greenberg L, Hatini V. 2010. Systematic expression and loss-of-function analysis defines spatially restricted requirements for Drosophila RhoGEFs and RhoGAPs in leg morphogenesis. Mech Dev. 128: 5-17. books

Guo Z, Packard A, Krolewski RC, Harris MT, Manglapus GL, Schwob JE. 2010. J Comp Neurol. 518: 4395-4418. books

Hone AJ, Whiteaker P, Mohn JL, Jacob MH, Michael McIntosh J. 2010. Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling α7 nicotinic acetylcholine receptors. J Neurochem. 114: 994-1006 books

Keller PJ, Lin AF, Arendt LM, Klebba I, Jones AD, Rudnick JA, Dimeo TA, Gilmore H, Jefferson DM, Graham RA, Naber SP, Schnitt S, Kuperwasser C. 2010. Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines. Breast Cancer Res. 12: R87. books

Kluge JA, Thurber A, Leisk GG, Kaplan DL, Dorfmann AL. 2010. A model for the stretch-mediated enzymatic degradation of silk fibers. J Mech Behav Biomed Mater. 3: 538-547. books

Kubilus JK, Linsenmayer TF. 2010. Developmental corneal innervation: interactions between nerves and specialized apical corneal epithelial cells. Invest Ophthalmol Vis Sci. 51: 782-789. books

Kubilus JK, Linsenmayer TF. 2010. Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2. Dev Biol. 344: 172-184. books

Ma KN, Cashman SM, Sweigard JH, Kumar-Singh R. 2010. Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration. Invest Ophthalmol Vis Sci. 51: 6776-6783. books

Markowska AI, Liu FT, Panjwani N. 2010. Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med. 207: 1981-1993. books

McCready J, Arendt LM, Rudnick JA, Kuperwasser C. 2010. The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis. Breast Cancer Res. 12: 205. books

Rosenberg MM, Yang F, Mohn JL, Storer EK, Jacob MH. 2010. The postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic synapses in vivo. J Neurosci. 30: 11073-11085. books

Russo JW, Castellot JJ. 2010. CCN5: biology and pathophysiology. J Cell Commun Signal. 4: 119-130.  books

Saravanan C, Cao Z, Head SR, Panjwani N. 2010. Analysis of differential expression of glycosyltransferases in healing corneas by glycogene microarrays.Glycobiology 20: 13-23. books 

Sweigard JH, Cashman SM, Kumar-Singh R. 2010. Adenovirus vectors targeting distinct cell types in the retina. Invest Ophthalmol Vis Sci. 51: 2219-2228. books

Sowalsky AG, Alt-Holland A, Shamis Y, Garlick JA, Feig LA. 2010. RalA suppresses early stages of Ras-induced squamous cell carcinoma progression. Oncogene 29: 45-55. Abstract in PubMed

Wiesman KC, Wei L, Baughman C, Russo J, Gray MR, Castellot JJ. 2010. CCN5, a secreted protein, localizes to the nucleus. J Cell Commun Signal. 4: 91-98. Abstract in PubMed

2009


Beazley KE, Canner JP, Linsenmayer TF. 2009. Developmental regulation of the nuclear ferritoid-ferritin complex of avian corneal epithelial cells: roles of systemic factors and thyroxine. Exp Eye Res. 89: 854-862. books

Beazley KE, Nurminskaya M, Linsenmayer TF. 2009. Phosphorylation regulates the ferritoid-ferritin interaction and nuclear transport. J Cell Biochem. 107: 528-536. books

Cairns DM, Lee PG, Uchimura T, Seufert C, Kwon H, Zeng L. 2009. The role of muscle cells in regulating cartilage matrix production. J Orthop Res. Epub ahead of print. Abstract in PubMed

DiMeo TA, Anderson K, Fen C, Padkhe P, Naber S, Perou C, Kuperwasser C. 2009. A novel lung metastasis signature links wnt signaling with cancer cell self-renewal and the epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res. 69: 5364-5373. books 

Diskin S, Cao Z, Leffler H, Panjwani N. 2008. The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. Glycobiology 19: 29-37. books

Diskin S, Panjwani N. 2008. Carbohydrate-based recognition systems in primary open angle glaucoma.  Curr Org Chem. 12:  911-917.

Greenberg L,  Hatini V. 2009. Essential roles for lines in mediating leg and antennal proximodistal patterning and generating a stable Notch signaling interface at segment borders. Dev Biol. 330: 93–104.  books

Hewitt KJ, Shamis Y, Carlson MW, Aberdam E, Aberdam D, Garlick JA. 2009. Three-dimensional epithelial tissues generated from human embryonic stem cells. Tissue Eng Part A 15: 3417-3426. books

Myers JP, vom Saal FS, Akingbemi BT, Arizono K, Belcher S, Colborn T, Chahoud I, Crain DA, Farabollini F, Guillette LJ Jr, Hassold T, Ho SM, Hunt PA, Iguchi T, Jobling S, Kanno J, Laufer H, Marcus M, McLachlan JA, Nadal A, Oehlmann J, Olea N, Palanza P, Parmigiani S, Rubin BS, Schoenfelder G, Sonnenschein C, Soto AM, Talsness CE, Taylor JA, Vandenberg LN, Vandenbergh JG, Vogel S, Watson CS, Welshons WV, Zoeller RT. 2009. Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect. 117:309-315. books

Nurminskaya MV, Talbot CJ, Nurminsky DI, Beazley KE, Linsenmayer TF. 2009. Nuclear ferritin: a ferritoid-ferritin complex in corneal epithelial cells. Invest Ophthalmol Vis Sci. 50: 3655-3661. books

Rosenberg M, Yang F, Giovanni M, Mohn JL, Temburni MK, Jacob MH. 2008. Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex. Mol Cell Neurosci. 38: 138- 152. books  

Saravanan C, Liu FT, Gipson IK, Panjwani N. 2009. Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on α3β1 integrin. J Cell Sci. 122: 3684-3693. books

Saravanan C, Cao Z, Head SR, Panjwani N. 2009. Detection of differentially expressed wound-healing-related glycogenes in galectin-3-deficient mice. Invest Ophthalmol Vis Sci. 50: 5690-5696. books

Vandenberg LN, Maffini MV, Sonnenschein C, Rubin BS, Soto AM. 2009. Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption. Endocr Res. 30: 75-95. books

Wei L, McKeon F, Russo JW, Lemire J, Castellot J. 2009. Domain-and species-specific monoclonal antibodies recognize the Von Willebrand Factor-C domain of CCN5. J Cell Commun Signal. 3: 65-77. books

 

2008


Alt-Holland A, Shamis Y, Riley KN, DesRochers TM, Fusenig NE, Herman IM, Garlick JA. 2008. E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J Invest Dermatol. 128: 2498-2507. books

Bandyopadhyay A, Kubilus JK, Crochiere ML, Linsenmayer TF, Tabin CJ. 2008. Identification of unique molecular subdomains in the perichondrium and periosteum and their role in regulating gene expression in the underlying chondrocytes. Dev Biol. 321: 162-174. books

Beazley KE, Nurminskaya M, Talbot CJ, Linsenmayer TF. 2008. Corneal epithelial nuclear ferritin: developmental regulation of ferritin and its nuclear transporter ferritoid. Dev Dyn. 237: 2529-2541. books

Cairns DM, Sato ME, Lee PG, Lassar AB, Zeng L. 2008. A gradient of Shh establishes mutually repressing somitic cell fates induced by Nkx3.2 and Pax3. Dev Biol. 323: 152-165. Abstract in PubMed

Cao Z, Saravanan C, Goldstein MH, Wu HK, Pasricha G, Sharma S, Panjwani N. 2008.  Human tears inhibit Acanthamoeba-induced cytopathic effect.  Arch Ophthalmol. 126: 348-352. books

Crochiere ML, Kubilus JK, Linsenmayer TF. 2008. Perichondrial-mediated TGF-β regulation of cartilage growth in avian long bone development. Int J Dev. 52: 63-70. books

Jang W, Lambropoulos J, Woo JK, Peluso CE, Schwob JE. 2008. Maintaining epitheliopoietic potency when culturing olfactory progenitors. Exp Neurol. Epub ahead of print. books

Krause S, Maffini MV, Soto AM, Sonnenschein C. 2008. A novel 3D in vitro culture model to study stromal-epithelial interactions in the mammary gland. Tissue Eng Part C Methods 14: 261-271. books

Nusinow D, Greenberg L, Hatini V. 2008.  Reciprocal roles for bowl and lines in specifying the peripodial epithelium and the disc proper of the Drosophila wing primordium.  Development 135: 3031-3041. books 

Saravanan C, Cao Z, Kumar J, Qiu J, Plaut A, Newburg D, Panjwani N. 2008. Milk components inhibit Acanthamoeba-induced cytopathic effect. Invest Ophthalmol Vis Sci. 49: 1010-1015. books

Soto AM, Vandenberg LN, Maffini MV, Sonnenschein C. 2008. Does breast cancer start in the womb? Basic Clin Pharmacol Toxicol. 102: 125-133. books

Vandenberg LN, Maffini MV, Schaeberle CM, Ucci AA, Sonnenschein C, Rubin BS, Soto AM. 2008. Perinatal exposure to the xenoestrogen bisphenol-A induces mammary intraductal hyperplasias in adult CD-1 mice. Reprod Toxicol. 26: 210-219. books

Zhang J, Zhu J, Valverde P, Li L, Pageau S, Tu Q, Nishimura R, Yoneda T, Yang P, Zheng W, Ma W, Chen J. 2008. Phenotypic analysis of Dlx5 overexpression in post-natal bone. J Dent Res. 87: 45-50. books

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