Cancer Biology

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Vision for Training


Researchers in this specialization track will investigate how genetic and environmental factors result in cancer through the molecular and cellular analyses of cancer stem cells, the disruption of cellular growth control or organismal development. Collaborative studies wedding together clinicians and laboratory scientists not only will help to unveil the biological mechanisms that govern normal and abnormal cellular processes; but, successful outcomes will enable the development of diagnostic tests for early detection, better diagnostic methods using biological markers, more effective treatments and prevention strategies that may offer ‘next generation’ and ‘personalized’ therapeutics.


Faculty with Active Research Programs


Brent Cochran, PhD, Concentration Leader - Glioblastoma stem cells and molecular mechanisms of brain cancer Send an e-mail  PI Profile

Karl Munger, PhD, Concentration Leader - HPV-mediated oncogenesis  Send an e-mail  PI Profile

Lidija Covic, PhD - Protease activated receptors and cancer metastasis  Send an e-mail  PI Profile    

Alexei Degterev, PhD - Mechanisms of cell death using small molecule and drug probes  Send an e-mail  PI Profile

Michael Forgac, PhD - Mechanism of regulation of vacuolar acidification  Send an e-mail  PI Profile

Marta Gaglia, PhD - Virus - host interaction in KSHV infection  Send an e-mail  PI Profile

Jonathan Garlick, DDS, PhD - Cell-cell interaction in squamous cell carcinoma; stem cells and tissue regeneration Send an e-mail  PI Profile

Ira Herman, PhD, - Angiogenesis Send an e-mail  PI Profile

Philip Hinds, PhD - Retinoblastoma pathway in differentiation, senescence, and cancer  Send an e-mail  PI Profile

Guo-fu Hu, PhD - Angiogenesis in cancer and neurodegeneration Send an e-mail  PI Profile

Athan Kuliopulos, MD, PhD - Protease activated receptors in vascular biology and cancer  Send an e-mail  PI Profile

Rajendra Kumar-Singh, PhD - Gene therapy for inherited retinal disorders Send an e-mail  PI Profile

Charlotte Kuperwasser, PhD - Molecular mechanisms of breast cancer development Send an e-mail  PI Profile 

Malavika Raman, PhD - Mechanisms of protein homeostasis  Send an e-mail PI Profile

Ana Soto, MD - Control of cell proliferation Send an e-mail  PI Profile

Philip Tsichlis, MD - Molecular mechanisms of leukemogenesis and gene discovery  Send an e-mail   PI Profile

Amy Yee, PhD - Breast cancer, stem cells and transcriptional regulation  Send an e-mail  PI Profile 


Program Faculty Participating in Teaching


John Castellot, PhD - Mechanisms of smooth muscle proliferation Send an e-mail  PI Profile

Mark Ewen, PhD - Mammary gland development and tumorigenesis  Send an e-mail  PI Profile

Giannoula Klement, MD - Platelet-facilitated cell-cell communication in cancer  Send an e-mail  PI Profile

K Eric Paulson, PhD - ROS signaling and cancer  Send an e-mail  PI Profile

G Gary Sahagian, PhD - Lysosomal trafficking and function in cancer; organ-selective metastasis in breast cancer Send an e-mail  PI Profile

Brian Schaffhausen, PhD - Mechanism of neoplastic transformation  Send an e-mail  PI Profile

Gail Sonenshein, PhD - Signaling in breast cancer  Send an e-mail  PI Profile

Carlos Sonnenschein, MD - Proliferation of estrogen-dependent cells Send an e-mail  PI Profile

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research