Julia Yelick

julia

Julia Yelick
BS, Neuroscience
Dickinson  College
Carlisle, PA
PhD Student in Cell, Molecular & Developmental Biology
Yongjie Yang, PhD, Adviser

 

 

 

Astrocytes have recently been found to actively engage in neuronal signaling, as well as to play important roles in brain physiology and pathology. Astrocytes express an important membrane protein, Glutamate Transporter 1 (GLT-1), which becomes dysregulated in many neurological disorders. However, regulation of the expression of this transporter is unknown. My interest is to find microRNAs that regulate GLT-1, as well as determine how neuronal-mediated exosome signaling can modulate these microRNAs and subsequent GLT-1 expression. I aim to investigate my microRNA targets utilizing microarray, luciferase and viral techniques. Subsequent discovery of these microRNAs would provide a novel mechanism for modulating GLT1 expression, as well as provide the potential for drug development and future treatment of GLT-1 deficient diseases.

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research