Joshua Man


Joshua Man
BA, Biology
University of Southern California
Los Angeles, CA
MD, PhD Student in Cell, Molecular & Developmental Biology
Iris Jaffe, MD, PhD, Adviser




Our lab studies the role of vascular mineralocorticoid receptor (MR)-regulated genes in vascular function and disease. I am focusing on the mechanism by which MR in macrophages contributes to the initiation and propagation of cardiovascular disease in the setting of common risk factors. I am also working to study the effect that targeted therapies used in cancer have on the phosphoproteome and epigenome in specific cell types to explain differences in vascular toxicities among and within drug classes. The ultimate goal is use this approach to discover drugs that can serve as co-treatments and protect cancer patients from iatrogenic cardiovascular disease.

Back to the Jaffe Profile Page

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research