Elizabeth Smith


Elizabeth Smith
BS, Biochemistry
University of Massachusetts - Boston
Boston, MA 
Cell, Molecular & Developmental Biology PhD Student
Pamela Yelick, PhD Adviser




The reciprocal interactions between dental epithelial (DE) and dental mesenchymal (DM) cells is very important in tooth development. My thesis work is focused on developing an in vitro three dimensional (3D) tooth model that incorporates a nanofabricated gelatin methacrylate (GelMA) scaffold and both DE and DM cell types. With this model, we will be able to readily examine cues regulating various stages of tooth development, as well as the interactions between normal and diseased DE and DM cells. The proposed 3D tooth organ model is anticipated to have wide spread use in studying the development of a variety of other organs, which also are the result of reciprocal epithelial/mesenchymal cell interactions.

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