Student Publications


Davel AP, Lu Q, Moss ME, Rao S, Anwar IJ, DuPont JJ, Jaffe IZ. 2018. J Am Heart Assoc 7: pii: e007675. doi: 10.1161/JAHA.117.007675. books

Del Signore SJ, Cilla R, Hatini V. 2018. The WAVE regulatory complex and branched F-actin counterbalance contractile force to control cell shape and packing in the Drosophila eye. Dev Cell Epub ahead of print. books

Fiaturi N, Russo JW, Nielsen HC, Castellot JJ Jr. 2017. CCN5 in alveolar epithelial proliferation and differentiation during neonatal lung oxygen injury. J Cell Commun Signal. Epub ahead of print.  Abstract in PubMed

Hui Mingalone CK, Liu Z, Hollander JM, Garvey KD, Gibson AL, Banks RE, Zhang M, McAlindon TE, Nielsen HC, Georgakoudi I, Zeng L. 2018. Bioluminescence and second harmonic generation imaging reveal dynamic changes in the inflammatory and collagen landscape in early osteoarthritis. Lab Invest. Epub ahead of print. Abstract in PubMed

Kim SK, McCurley AT, DuPont JJ, Aronovitz M, Moss ME, Stillman IE, Karumanchi SA, Christou DD, Jaffe IZ. 2018. Smooth muscle cell-mineralocorticoid receptor as a mediator of cardiovascular stiffness with aging. Hypertension Epub ahead of print. books

Ni TK, Elman JS, Jin DX, Gupta PB, Kuperwasser C. 2018. Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon. Sci Rep. 8: 1415. books

Rodriguez MJ, Dixon TA, Cohen E, Huang W, Omenetto FG, Kaplan DL. 2018. 3D freeform printing of silk fibroin. Acta Biomater. Epub ahead of print. books


Breindel JL, Skibinski A, Sedic M, Wronski-Campos A, Zhou W, Keller PJ, Mills J, Bradner J, Onder T, Kuperwasser C. 2017. Epigenetic reprogramming of lineage-committed human mammary epithelial cells requires DNMT3A and loss of DOT1L. Stem Cell Reports. Epub ahead of print.  Abstract in PubMed

Coleman JH, Lin B, Schwob JE. 2017. Dissecting LSD1-dependent neuronal maturation in the olfactory epithelium. Comp Neurol. Epub ahead of print. books

Diaz-Otero JM, Fisher C, Downs K, Moss ME, Jaffe IZ, Jackson WF, Dorrance AM. 2017. Endothelial mineralocorticoid receptor mediates parenchymal arteriole and posterior cerebral artery remodeling during angiotensin II-induced hypertension. Hypertension Epub ahead of print.  books

Du C, Collins W, Cantley W, Sood D, Kaplan, DL. 2017. Tutorials for electrophysiological recordings in tissue engineering. ACS Biomaterials Science & Engineering. Abstract in PubMed

Gibson AL, Hui Mingalone CK, Foote AT, Uchimura T, Zhang M, Zeng L. 2017. Wnt7a inhibits IL-1β induced catabolic gene expression and prevents articular cartilage damage in experimental osteoarthritis. Sci Rep. 7: 41823.  Abstract in PubMed

Herrick DB, Lin B, Peterson J, Schnittke N, Schwob JE. 2017. Notch1 maintains dormancy of olfactory horizontal basal cells, a reserve neural stem cell. Proc Natl Acad Sci USA Epub ahead of print. books

Khayat A, Monteiro N, Smith EE, Pagni S, Zhang W, Khademhosseini A, Yelick PC. 2017. GelMA-encapsulated hDPSCs and HUVECs for dental pulp regeneration. J Dent Res. 96: 192-199. Abstract in PubMed

LaBonty M, Yelick PC. 2017. Animal models of Fibrodysplasia Ossificans Progressiva. Dev Dyn. Epub ahead of print. Abstract in PubMed

Lin B, Coleman JH, Peterson JN, Zunitch MJ, Jang W, Herrick DB, Schwob JE. 2017. Injury induces endogenous reprogramming and dedifferentiation of neuronal progenitors to multipotency. Cell Stem Cell Epub ahead of print. books

Marzolla V, Armani A, Mammi C, Moss ME, Pagliarini V, Pontecorvo L, Antelmi A, Fabbri A, Rosano G, Jaffe IZ, Caprio M. 2017. Essential role of ICAM-1 in aldosterone-induced atherosclerosis. Int J Cardiol. 232: 233-242.  Abstract in PubMed

Morel L, Chiang MSR, Higashimori H, Shoneye T, Iyer LK, Yelick J, Tai A, Yang Y. 2017. Molecular and functional properties of regional astrocytes in the adult brain. J Neurosci. 37: 8706-8717.  Abstract in PubMed

Nakamura DS, Hollander JM, Uchimura T, Nielsen HC, Zeng L. 2017. Pigment epithelium-derived factor (PEDF) mediates cartilage matrix loss in an age-dependent manner under inflammatory conditions. BMC Musculoskelet Disord. 18: 39.  Abstract in PubMed

Olsen SN, Wronski A, Castaño Z, Dake B, Malone C, De Raedt T, Enos M, DeRose YS, Zhou W, Guerra S, Loda M, Welm A, Partridge AH, McAllister SS, Kuperwasser C, Cichowski K. 2017. Loss of RasGAP tumor suppressors underlies the aggressive nature of luminal B breast cancers. Cancer Discov. 7: 202-217.  books

Peterson JN, Lin B, Shin J, Phelan PJ, Tsichlis P, Schwob JE, Bullock PA. 2017. The Replication of JCV DNA in the G144 oligodendrocyte cell line is dependent upon Akt. J Virol. Epub ahead of print.  books

Salvador AM, Moss ME, Aronovitz M, Mueller KB, Blanton RM, Jaffe IZ, Alcaide P. 2017. Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation. Physiol Rep. 5 (12).  books

Thurber AE, Nelson M, Frost CL, Levin M, Brackenbury WJ, Kaplan DL. 2017. IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines. Oncotarget Epub ahead of print.  books

Smith EE, Yelick PC. 2017. Progress in bioengineered whole tooth research: From bench to dental patient chair. Curr Oral Health. 3: 302-308. Abstract in PubMed

Smith EE, Zhang W, Schiele NR, Khademhosseini A, Kuo CK, Yelick PC. 2017. Developing a biomimetic tooth bud model. J Tissue Eng Regen Med. Epub ahead of print. Abstract in PubMed

Uchimura T, Hollander JM, Nakamura DS, Liu Z, Rosen CJ, Georgakoudi I, Zeng L. 2017. An essential role for IGF2 in cartilage development and glucose metabolism during postnatal long bone growth. Development 144: 3533-3546. Abstract in PubMed

Yeo AT, Charest A. 2017. Immune checkpoint blockade biology in mouse models of glioblastoma. J Cell Biochem. Epub ahead of print. books


Chen WS, Cao Z, Sugaya S, Lopez MJ, Sendra VG, Laver N, Leffler H, Nilsson UJ, Fu J, Song J, Xia L, Hamrah P, Panjwani N. 2016. Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3. Nat Commun. 7: 11302. books

Gerami-Naini B, Smith A, Maione AG, Kashpur O, Carpinito G, Veves A, Mooney DJ, Garlick JA. 2016. Generation of induced pluripotent stem sells from diabetic foot ulcer fibroblasts using a nonintegrative Sendai virus. Cell Reprogram. 18: 214-223. books

Gross K, Wronski A, Skibinski A, Phillips S, Kuperwasser C. 2016. Cell fate decisions during breast cancer development. J Dev Biol. 4: 4.   books

Jena N, Sheng J, Hu JK, Li W, Zhou W, Lee G, Tsichlis N, Pathak A, Brown N, Deshpande A, Luo C, Hu GF, Hinds PW, Van Etten RA, Hu MG. 2016. CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T cell acute lymphoblastic leukemia. Leukemia 30: 1033-1043. books

Jia G, Habibi J, Aroor AR, Martinez-Lemus LA, DeMarco VG, Ramirez-Perez FI, Sun Z, Hayden MR, Meininger GA, Barrett Mueller KV, Jaffe IZ, Sowers JR. 2016. Endothelial mineralocorticoid receptor mediates diet induced aortic stiffness in females. Circ Res. 118: 935-943. books

Liang L, Stone RC, Stojadinovic O, Ramirez H, Pastar I, Maione AG, Smith A, Yanez V, Veves A, Kirsner RS, Garlick JA, Tomic-Canic M. 2016. Integrative analysis of miRNA and mRNA paired expression profiling of primary fibroblast derived from diabetic foot ulcers reveals multiple impaired cellular functions. Wound Regen Repair. 24: 943-953.  books

Liu Z, Pouli D, Sood D, Sundarakrishnan A, Hui Mingalone CK, Arendt LM, Alonzo C, Quinn KP, Kuperwasser C, Zeng L, Schnelldorfer T, Kaplan DL, Georgakoudi I. 2016. Automated quantification of three-dimensional organization of fiber-like structures in biological tissues. Biomaterials 116: 34-47.  Abstract in PubMed

Maione AG, Smith A, Kashpur O, Yanez V, Knight E, Mooney DJ, Veves A, Tomic-Canic M, Garlick JA. 2016. Altered ECM deposition by diabetic foot ulcer-derived fibroblasts implicates fibronectin in chronic wound repair. Wound Repair Regen. 24: 630-643.  books

Monteiro N, Smith EE, Angstadt S, Zhang W, Khademhosseini A, Yelick PC. 2016. Dental cell sheet biomimetic tooth bud model. Biomaterials 106: 167-179. Abstract in PubMed

Moss BJ, Park L, Dahlberg CL, Juo P. 2016. The CaM kinase CMK-1 mediates a negative feedback mechanism coupling the C. elegans glutamate receptor GLR-1 with its own transcription. PLoS Genet. 12: e1006180. Abstract in PubMed

Packard AI, Lin B, Schwob JE. 2016. Sox2 and Pax6 play counteracting roles in regulating neurogenesis within the murine olfactory epithelium. PLoS One 11: e0155167. books

Sampson JF, Suryawanshi A, Chen WS, Rabinovich GA, Panjwani N. 2016. Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling. Immunol Cell Biol. 94: 213-219.   books

Sedic M, Kuperwasser C. 2016. BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer. Cell Cycle 15: 621-627.   books

Sweeney MF, Hasan N, Soto AM, Sonnenschein C. 2016. Environmental endocrine disruptors: Effects on the human male reproductive system. Rev Endocr Metab Disord. 16: 341-357. books

Uchimura T, Foote AT, Markel DC, Ren W, Zeng L. 2016. The chondroprotective role of erythromycin in a murine joint destruction model. Cartilage 7(4):373-387. Abstract in PubMed

Zhou W, Ni TK, Wronski A, Glass B, Skibinski A, Beck A, Kuperwasser C. 2016. The SIRT2 deacetylase stabilizes Slug to control malignancy of basal-like breast cancer. Cell Rep. 17: 1302-1317. books


Burman B, Zhang ZZ, Pegoraro G, Lieb JD, Misteli T. 2015. Histone modifications predispose genome regions to breakage and translocation. Genes Dev. 29: 1393-1402.   Abstract in PubMed

Burman B, Misteli T, Pegoraro G. 2015. Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging. Genome Biol. 16: 146. Abstract in PubMed

Cao Z, Saravanan C, Chen WS, Panjwani N. 2015. Examination of the role of galectins in cell migration and re-epithelialization of wounds. Methods Mol Biol. 1207: 317-326. books

Chen WS, Cao Z, Krishnan C, Panjwani N. 2015. Verteporfin without light stimulation inhibits YAP activation in trabecular meshwork cells: Implications for glaucoma treatment. Biochim Biophys Res Commun. 466: 221-225. books

Chen W, Cao Z, Truong L, Sugaya S, Panjwani N. 2015. Fingerprinting of galectins in normal, P. aeruginosa-infected and chemically burned mouse corneas. Invest Ophthalmol Vis Sci. 56: 515-525. books

Chetty A, Bennett M, Dang L, Nakamura D, Cao GJ, Mujahid S, Volpe M, Herman I, Becerra SP, Nielsen HC. 2015. Pigment epithelium-derived factor mediates impaired lung vascular development in neonatal hyperoxia. Am J Respir Cell Mol Biol. 52: 295-303. Abstract in PubMed

Chwalek K, Sood D, Cantley WL, White JD, Tang-Schomer M, Kaplan DL. 2015. Engineered 3D silk-collagen-based model of polarized neural tissue. J Vis Exp. (105): e52970. books

de Madrid BH, Greenberg L, Hatini V. 2015. RhoGAP68F controls transport of adhesion proteins in Rab4 endosomes to modulate epithelial morphogenesis of Drosophila leg discs. Dev Biol. 399: 283-295. books

Gilbert MA, Lin B, Peterson J, Jang W, Schwob JE. 2015. Neuregulin1 and ErbB expression in the uninjured and regenerating olfactory mucosa. Gene Exp Patterns 19:108-119. books

Jia G, Habibi J, DeMarco VG, Martinez-Lemus LA, Ma L, Whaley-Connell AT, Aroor AR, Domeier TL, Zhu Y, Meininger GA, Mueller KB, Jaffe IZ, Sowers JR. 2015. Endothelial mineralocorticoid receptor deletion prevents diet-induced cardiac diastolic dysfunction in females. Hypertension 66: 1159-1167. books

Kwon H, Rainbow RS, Sun L, Hui CK, Cairns DM, Preda RC, Kaplan DL, Zeng L. 2015. Scaffold structure and fabrication method affect pro-inflammatory milieu in 3D-cultured chondrocytes. J Biomed Mater Res A. 103: 534-544. books

Leahy AA, Esfahani SA, Foote AT, Hui CK, Rainbow RS, Nakamura DS, Tracey BH, Mahmood U, Zeng L. 2015. Following the trajectory of osteoarthritis development through serial near infrared fluorescence imaging of MMP activities. Arthritis Rheumatol. 67: 442-453. books

Maione AG, Brudno Y, Stojadinovic O, Park LK, Smith A, Tellechea A, Leal EC, Kearney CJ, Veves A, Tomic-Canic M, Mooney D, Garlick J. 2015. 3D human tissue models that incorporate diabetic foot ulcer-derived fibroblasts mimic in vivo features of chronic wounds. Tissue Eng Part C Methods 21: 499-508.  books

Mazumdar S, Arendt LM, Phillips S, Sedic M, Kuperwasser C, Gill G. 2015. CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer. PLoS One 10: e0121281. books

Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV 2015. Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development 142: 258-267. books

Moss ME, Jaffe IZ. 2015. Mineralocorticoid receptors in the pathophysiology of vascular inflammation and atherosclerosis. Front Endocrinol (Lausanne) 6: 153. books

Mueller KB, Bender SB, Hong K, Yang Y, Aronovitz M, Jaisser F, Hill MA, Jaffe IZ. 2015. Endothelial mineralocorticoid receptors differentially contribute to coronary and mesenteric vascular function without modulating blood pressure. Hypertension 66: 988-997.  books

Pinacho R, Saia G, Meana JJ, Gill G, Ramos B. 2015. Transcription factor SP4 phosphorylation is altered in the postmortem cerebellum of bipolar disorder and schizophrenia subjects. Eur Neuropsychopharmacol. pii: S0924-977X(15)00155-8. books

Reeves AR, Spiller KL, Freytes DO, Vunjak-Novakovic G, Kaplan DL. 2015. Controlled release of cytokines using silk-biomaterials for macrophage polarization. Biomaterials 73:272-283.  books

Sampson JF, Hasegawa E, Mulki L, Suryawanshi A, Jiang S, Chen WS, Rabinovich GA, Connor KM, Panjwani N. 2015. Galectin-8 ameliorates murine autoimmune ocular pathology and promotes a regulatory T cell response. PLoS One 10: e130772.  books

Schnittke N, Herrick DB, Lin B, Peterson J, Coleman JH, Packard AI, Jang W, Schwob JE. 2015. Transcription factor p63 controls the reserve status but not the stemness of horizontal basal cells in the olfactory epithelium. Proc Natl Acad Sci USA 112: E5068-E5077.  books

Schubert SM, Arendt LM, Zhou W, Baig S, Walter SR, Buchsbaum RJ, Kuperwasser C, Walt DR. 2015. Ultra-sensitive protein detection via single molecule arrays towards early stage cancer monitoring. Sci Rep. 5: 11034.  books

Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, Keller PJ, Glover E, Richardson AL, Cowan J, Toland AE, Ravichandran K, Riethman H, Naber SP, Näär AM, Blasco MA, Hinds PW, Kuperwasser C. 2015. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 6: 7505.   books

Skibinski A, Kuperwasser C. 2015. The origin of breast tumor heterogeneity. Oncogene 34: 5309-5316. books

Sugaya S, Chen WS, Cao Z, Kenyon KR, Yamaguchi T, Omoto M, Hamrah P, Panjwani N. 2015. Comparison of galectin expression signatures in rejected and accepted murine corneal allografts. Cornea 34: 675-681. books

Sun X, Pinacho R, Saia G, Punko D, Meana JJ, Ramos B, Gill G. 2015. Transcription factor Sp4 regulates expression of nervous wreck 2 to control NMDAR1 levels and dendrite patterning. Dev Neurobiol. 75: 93-108. books

Thurber AE, Omenetto FG, Kaplan DL. 2015. In vivo bioresponses to silk proteins. Biomaterials. 71: 145-157.   books

Uchimura T, Foote AT, Smith EL, Matzkin EG, Zeng L. 2015. Insulin-like growth factor II (IGF-II) inhibits IL-1β-induced cartilage matrix loss and promotes cartilage integrity in experimental osteoarthritis. J Cell Biochem. 116: 2858-2869. books


Barrett Mueller K, Lu Q, Mohammad NN, Luu V, McCurley A, Williams GH, Adler GK, Karas RH, Jaffe IZ. 2014. Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology. 155: 4461-4472. books

Burgess RC, Burman B, Kruhlak MJ, Misteli T. 2014. Activation of DNA damage response signaling by condensed chromatin. Cell Rep. 9:1703-1717. books

Canner JP, Linsenmayer TF, Kubilus JK. 2014. Developmental regulation of trigeminal TRPA1 by the cornea. Invest Ophthalmol Vis Sci. 56: 29-36. books

Hewitt KJ, Shamis Y, Gerami-Naini B, Garlick JA. 2014. Strategies for oral mucosal repair by engineering 3D tissues with pluripotent stem cells. Adv Wound Care (New Rochelle). 3: 742-750.  books

Holbrook EH, Iwema CL, Peluso CE, Schwob JE. 2014. The regeneration of P2 olfactory sensory neurons Is selectively impaired following methyl bromide lesion. Chem Senses. 39: 601-616. books

Kottakis F, Foltopoulou P, Sanidas I, Keller P, Wronski A, Dake BT, Ezell SA, Shen Z, Naber SP, Hinds PW, McNiel EA, Kuperwasser C, Tsichlis PN. 2014. NDY1/KDM2B functions as a master regulator of Polycomb complexes and controls self-renewal of breast cancer stem cells. Cancer Res. 74: 3935-3946. books

Lalonde J, Saia G, Gill G. 2014. Store-operated calcium entry promotes the degradation of the transcription factor sp4 in resting neurons. Sci Signal. 7: ra51. books

Mohn JL, Alexander J, Pirone A, Palka CD, Lee SY, Mebane L, Haydon PG, Jacob MH. 2014. Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities. Mol Psychiatry. 19: 133-142. books

Mohn JL, Alexander J, Pirone A, Palka CD, Lee SY, Mebane L, Haydon PG, Jacob MH. 2014. New molecular insights into cognitive and autistic-like disabilities. Mol Psychiatry. 19: 1053. books

Myers RB, Wei L, Castellot JJ Jr. 2014. The matricellular protein CCN5 regulates podosome function via interaction with integrin αvβ 3. J Cell Commun Signal. 8: 135-146. books

Park LK, Maione AG, Smith A, Gerami-Naini B, Iyer LK, Mooney DJ, Veves A, Garlick JA. 2014. Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts. Epigenetics. 9: 1339-1349. books

Phillips S, Prat A, Sedic M, Proia T, Wronski A, Mazumdar S, Skibinski A, Shirley SH, Perou CM, Gill G, Gupta PB, Kuperwasser C. 2014. Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation. Stem Cell Reports. 2: 633-647. books

Saia G, Lalonde J, Sun X, Ramos B, Gill G. 2014. Phosphorylation of the transcription factor Sp4 is reduced by NMDA receptor signaling. J Neurochem. 129: 743-752. books

Silfa-Mazara F, Mujahid S, Thomas C, Vong T, Larsson I, Nielsen HC, Volpe MV. 2014. Oxygen differentially affects the hox proteins Hoxb5 and Hoxa5 altering airway branching and lung vascular formation. J Cell Commun Sig. 8: 231-244. Abstract in PubMed

Skibinski A, Breindel JL, Prat A, Galván P, Smith E, Rolfs A, Gupta PB, Labaer J, Kuperwasser C. 2014. The hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment. Cell Rep. 6: 1059-1072. books

Tang-Schomer MD, Davies P, Graziano D, Thurber AE, Kaplan DL. 2014. Neural circuits with long-distance axon tracts for determining functional connectivity. J Neurosci Methods. 222: 82-90. books

Zhao C, Andreeva V, Gibert Y, Labonty M, Lattanzi V, Prabhudesai S, Zhou Y, Zon L, McCann KL, Baserga S, Yelick PC. 2014. Tissue specific roles for the ribosome biogenesis factor wdr43 in zebrafish development. PLoS Genetics. 10: e1004074. books


Barrett K, McCurley A, Jaffe IZ. 2013. Direct contribution of vascular mineralocorticoid receptors to blood pressure regulation. Clin Exp Pharmacol Physiol. 40: 902-909. books

Cairns DM, Pignolo RJ, Uchimura T, Brennan TA, Lindborg CM, Xu M, Kaplan FS, Shore EM, Zeng L.. 2013. Somitic disruption of GNAS in chick embryos mimics progressive osseous heteroplasia. J Clin Invest. 123: 3624-3633. books

Hatini V, Kula E, Nusinow D, Del Signore SJ. 2013. Essential roles for stat92E in expanding and patterning theproximodistalaxis of the Drosophila wing imaginal disc. Dev Biol. 378: 38-50. books

Krolewski RC, Packard A, Schwob JE. 2013. Global expression profiling of globose basal cells and neurogenic progression within the olfactory epithelium. J Comp Neurol. 521: 833-859. books

Kwon H, Sun L, Cairns DM, Rainbow RS, Preda RC, Kaplan DL, Zeng L. 2013. The influence of scaffold material on chondrocytes in inflammatory conditions. Acta Biomater. 9: 6563-6575. books

McGraw AP, Bagley J, Chen W-S, Galayda C, Nickerson H, Armani A, Caprio M, Carmeliet P, Jaffe IZ, 2013. Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism. J Am Heart Assoc. 2: e000018. Abstract in PubMed

McLaughlin SK, Olsen SN, Dake B, De Raedt T, Lim E, Bronson RT, Beroukhim R, Polyak K, Brown M, Kuperwasser C, Cichowski K. 2013. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell. 24: 365-378. books

Mujahid S, Logvinenko T, Volpe MV, Nielsen HC. 2013. miRNA regulated pathways in late stage murine lung development. BMC Dev Biol. 13: 13.  books

Mujahid S, Nielsen HC, Volpe MV. 2013. MiR-221 and miR-130a regulate lung airway and vascular development. PLoS One. 8: e55911. books

Rainbow RS, Kwon H, Foote AT, Preda RC, Kaplan DL, Zeng L. 2013. Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytes. Osteoarthritis Cartilage. 21: 990-998. books

Roukos V, Burman B, Misteli T. 2013. The cellular etiology of chromosome translocations. Curr Opin Cell Biol. 25: 357-364. books

Shamis Y, Silva EA, Hewitt KJ, Brudno Y, Levenberg S, Mooney DJ, Garlick JA. 2013. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo. PLoS One. 8: e83755. books

Volpe MV, Ramadurai SM, Mujahid S, Vong T, Brandao M, Wang KT, Pham LD, Nielsen HC. 2013. Regulatory interactions between androgens, Hoxb5, and TGFβ signaling in murine lung development. Biomed Res Int. 2013: 320249. books

Xie F, Fang C, Schnittke N, Schwob JE, Ding X. 2013. Mechanisms of permanent loss of olfactory receptor neurons induced by the herbicide 2,6-dichlorobenzonitrile: Effects on stem cells and noninvolvement of acute induction of the inflammatory cytokine IL-6. Toxicol Appl Pharmacol. 272: 598-607. books

Zhu C, Gupta A, Hall VL, Rayla AL, Christensen RG, Dake B, Lakshmanan A, Kuperwasser C, Stormo GD, Wolfe SA. 2013. Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases. Nucleic Acids Res. 41: 2455-2465. books


Cairns DM, Liu R, Sen M, Canner JP, Schindeler A, Little DG, Zeng L.2012. Interplay of Nkx3.2, sox9 and pax3 regulates chondrogenic differentiation of muscle progenitor cells. PLoS One 7: e39642. books

Del Signore SJ, Hayashia T, Hatini V. 2012. odd-skipped genes and lines organize the notum anterior-posterior axis using autonomous and non-autonomous mechanisms. Mech Dev. 129: 147-161. books

Demidova-Rice TN, Hamblin MR, Herman IM. 2012.  Acute and impaired wound healing: Pathophysiology and current methods for drug delivery, Part 2: Role of growth factors in normal and pathological wound healing: Therapeutic potential and methods of delivery. Adv Skin Wound Care 25: 349-370. books

Demidova-Rice TN, Hamblin MR, Herman IM. 2012. Acute and impaired wound healing: Pathophysiology and current methods for drug delivery, Part 1: Normal and chronic wounds: Biology, causes, and approaches to care. Adv Skin Wound Care 25: 304-314. books

Demidova-Rice TN, Wolf L, Deckenback J, Hamblin MR, Herman IM. 2012. Human platelet-rich plasma- and extracellular matrix-derived peptides promote impaired cutaneous wound healing in vivo. PLoS One 7: e32146. Abstract in PubMed

Desrochers TM, Shamis Y, Alt-Holland A, Kudo Y, Takata T, Wang G, Jackson-Grusby L, Garlick JA. 2012. The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma. Epigenetics 7: 1. Abstract in PubMed 

Diskin S, Chen WS, Cao Z, Gyawali S, Gong H, Soza A, González A, Panjwani N. 2012. Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signaling. PLoS One 7: e44400. Abstract in PubMed

Hewitt KJ, Garlick JA. 2012. Cellular reprogramming to reset epigenetic signatures. Mol Aspects Med. 34: 841-848. books

Hewitt KJ, Shamis Y, Knight E, Smith A, Maione A, Alt-Holland A, Sheridan SD, Haggarty SJ, Garlick JA. 2012. PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation. J Cell Sci. 125: 2276-2287. Abstract in PubMed

Krause S, Jondeau-Cabaton A, Dhimolea E, Soto AM, Sonnenschein C, Maffini MV. 2012. Dual regulation of breast tubulogenesis using extracellular matrix composition and stromal cells. Tissue Eng Part A 18: 520-532. Abstract in PubMed

Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE. 2012. Ascl1 (mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One 7: e51737. books

Myers RB, Rwayitare K, Richey L, Lem J, Castellot JJ Jr. 2012. CCN5 Expression in mammals. III. Early embryonic mouse development. J Cell Commun Signal. 6: 217-223. Abstract in PubMed

Peluso CE, Jang W, Dräger U, Schwob JE. 2012. Differential expression of components of the retinoic acid signaling pathway in the adult mouse olfactory epithelium. J Comp Neurol. 520: 3707-3726. Abstract in PubMed

Rudnick JA, Kuperwasser C. 2012. Stromal biomarkers in breast cancer development and progression. Clin Exp Metastasis. 29: 633-672. Abstract in PubMed

Shamis Y, Hewitt KJ, Bear SE, Alt-Holland A, Qari H, Margvelashvilli M, Knight EB, Smith A, Garlick JA. 2012. iPSC-derived fibroblasts demonstrate augmented production and assembly of extracellular matrix proteins. In Vitro Cell Dev Biol Anim. 48: 112-122. Abstract in PubMed


Alt-Holland A, Sowalsky AG, Szwec-Levin Y, Shamis Y, Hatch H, Feig LA, Garlick JA. 2011. Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src. J Invest Dermatol. 131: 2306-2315. Abstract in PubMed

Carlson M, Faria K, Shamis Y, Leman J, Ronfard V, Garlick J. 2011. Epidermal stem cells are preserved during commercial scale manufacture of a bilayered, living cellular construct (Apligraf®). Tissue Eng Part A. 17: 487-493. Abstract in PubMed

Demidova-Rice TN, Geevarghese A, Herman IM 2011. Bioactive peptides derived from vascular endothelial cell extracellular matrices promote microvascular morphogenesis and wound healing in vitro. Wound Repair Regen. 19: 59-70. Abstract in PubMed

Greenberg L, Hatini V. 2011. Systematic expression and loss-of-function analysis defines spatially restricted requirements for Drosophila RhoGEFs and RhoGAPs in leg morphogenesis. Mech Dev. 128: 5-17. books

Hoeing K, Zscheppang K, Mujahid S, Murray S, Volpe MV, Dammann CE, Nielsen HC. 2011. Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation. Biochim Biophys Acta. 1813: 480-491. books

Hewitt KJ, Shamis Y, Hayman RB, Margvelashvili M, Dong S, Carlson MW, Garlick JA. 2011. Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells. PLoS One 6: e17128. books

Hoeing K, Zscheppang K, Mujahid S, Murray S, Volpe MV, Dammann CE, Nielsen HC. 2011. Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation. Biochim Biophys Acta 1813: 480-491. books

Keller PJ, Arendt LM, Skibinski A, Logvinenko T, Klebba I, Dong S, Smith AE, Prat A, Perou CM, Gilmore H, Schnitt S, Naber SP, Garlick JA, Kuperwasser C.  2011. Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci USA 109: 2772-2777. books

Krolewski RC, Jang W, Schwob JE. 2011. The generation of olfactory epithelial neurospheres in vitro predicts engraftment capacity following transplantation in vivo. Exp Neurol. 229: 308-323. books

Markowska AI, Jefferies KC, Panjwani N. 2011. Galectin-3 protein modulates cell surface expression and activation of vascular endothelial growth factor receptor 2 in human endothelial cells. J Biol. Chem. 286: 29913-29921. books

Packard A, Giel-Moloney M, Leiter A, Schwob JE. 2011. Progenitor cell capacity of NeuroD1-expressing globose basal cells in the mouse olfactory epithelium. J Comp Neurol. 19: 3580-3596. books

Packard A*, Schnittke N*, Romano R, Sinha S, Schwob JE 2011. ΔNp63 regulates stem cell dynamics in the mammalian olfactory epithelium. J Neurosci. 31: 3748-8759  *equal contribution. books

Pageau SC, Sazonova OV, Wong JY, Soto AM, Sonnenschein C. 2011.  The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture. Biomaterials 32: 7169-7180. books

Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C. 2011. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell 8: 149-163.  Abstract in PubMed

Rudnick JA, Arendt LM, Klebba I, Hinds JW, Iyer V, Gupta PB, Naber SP, Kuperwasser C. 2011. Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells. PLoS One 6: e24605. Abstract in PubMed

Saitow C, Kaplan DL, Castellot JJ Jr. 2011. Heparin stimulates elastogenesis: application to silk-based vascular grafts. Matrix biol. 30: 346-355. Abstract in PubMed

Shamis Y, Hewitt KJ, Carlson MW, Margvelashvilli M, Dong S, Kuo CK, Daheron L, Egles C, Garlick JA. Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents. Stem Cell Res Ther. 2: 10. books

Sowalsky AG, Alt-Holland A, Shamis Y, Garlick JA, Feig LA. 2011. RalA function in dermal fibroblasts is required for the progression of squamous cell carcinoma of the skin. Cancer Res. 71: 758-767. Abstract in PubMed

Sweigard JH, Cashman SM, Kumar-Singh R. 2011. Adenovirus-mediated delivery of CD46 attenuates the alternative complement pathway on RPE: implications for age-related macular degeneration. Gene Ther. 18: 613-621.  books

Wang YZ, Yamagami T, Gan Q, Wang Y, Zhao T, Hamad S, Lott P, Schnittke N, Schwob JE, Zhou CJ. 2011. Canonical Wnt signaling promotes the proliferation and neurogenesis of peripheral olfactory stem cells during postnatal development and adult regeneration. J Cell Sci. 124: 1553-1563. books


Arendt LM, Rudnick JA, Keller PJ, Kuperwasser C. 2010. Stroma in breast development and disease. Semin Cell Dev Biol. 21: 11-18.  Abstract in PubMed

Cairns DM, Uchimura T, Kwon H, Lee PG, Seufert CR, Matzkin E, Zeng L. 2010. Muscle cells enhance resistance to pro-inflammatory cytokine-induced cartilage destruction. Biochem Biophys Res Commun. 392: 22-28. Abstract in PubMed

Cairns DM, Lee PG, Uchimura T, Seufert CR, Kwon H, Zeng L. 2010. The role of muscle cells in regulating cartilage matrix production. J Orthop Res. 28: 529-536. Abstract in PubMed

Egles C, Garlick JA, Shamis Y. 2010.  Three-dimensional human tissue models of wounded skin. Methods Mol Biol. 585: 345-359.  books

Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C. 2010. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc Natl Acad Sci USA 107: 21737-21742. books

Greenberg L, Hatini V. 2010. Systematic expression and loss-of-function analysis defines spatially restricted requirements for Drosophila RhoGEFs and RhoGAPs in leg morphogenesis. Mech Dev. 128: 5-17. books

Guo Z, Packard A, Krolewski RC, Harris MT, Manglapus GL, Schwob JE. 2010. J Comp Neurol. 518: 4395-4418. books

Hone AJ, Whiteaker P, Mohn JL, Jacob MH, Michael McIntosh J. 2010. Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling α7 nicotinic acetylcholine receptors. J Neurochem. 114: 994-1006. books

Keller PJ, Lin AF, Arendt LM, Klebba I, Jones AD, Rudnick JA, Dimeo TA, Gilmore H, Jefferson DM, Graham RA, Naber SP, Schnitt S, Kuperwasser C. 2010. Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines. Breast Cancer Res. 12: R87. books

Kluge JA, Thurber A, Leisk GG, Kaplan DL, Dorfmann AL. 2010. A model for the stretch-mediated enzymatic degradation of silk fibers. J Mech Behav Biomed Mater. 3: 538-547. books

Kubilus JK, Linsenmayer TF. 2010. Developmental corneal innervation: interactions between nerves and specialized apical corneal epithelial cells. Invest Ophthalmol Vis Sci. 51: 782-789. books

Kubilus JK, Linsenmayer TF. 2010. Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2. Dev Biol. 344: 172-184. books

Ma KN, Cashman SM, Sweigard JH, Kumar-Singh R. 2010. Decay accelerating factor (CD55)-mediated attenuation of complement: therapeutic implications for age-related macular degeneration. Invest Ophthalmol Vis Sci. 51: 6776-6783. books

Markowska AI, Liu FT, Panjwani N. 2010. Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med. 207: 1981-1993. books

McCready J, Arendt LM, Rudnick JA, Kuperwasser C. 2010. The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis. Breast Cancer Res. 12: 205. books

Rosenberg MM, Yang F, Mohn JL, Storer EK, Jacob MH. 2010. The postsynaptic adenomatous polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic synapses in vivo. J Neurosci. 30: 11073-11085. books

Russo JW, Castellot JJ. 2010. CCN5: biology and pathophysiology. J Cell Commun Signal. 4: 119-130.  books

Saravanan C, Cao Z, Head SR, Panjwani N. 2010. Analysis of differential expression of glycosyltransferases in healing corneas by glycogene microarrays. Glycobiology 20: 13-23. books 

Sweigard JH, Cashman SM, Kumar-Singh R. 2010. Adenovirus vectors targeting distinct cell types in the retina. Invest Ophthalmol Vis Sci. 51: 2219-2228. books

Sowalsky AG, Alt-Holland A, Shamis Y, Garlick JA, Feig LA. 2010. RalA suppresses early stages of Ras-induced squamous cell carcinoma progression. Oncogene 29: 45-55. Abstract in PubMed

Wiesman KC, Wei L, Baughman C, Russo J, Gray MR, Castellot JJ. 2010. CCN5, a secreted protein, localizes to the nucleus. J Cell Commun Signal. 4: 91-98. Abstract in PubMed


Beazley KE, Canner JP, Linsenmayer TF. 2009. Developmental regulation of the nuclear ferritoid-ferritin complex of avian corneal epithelial cells: roles of systemic factors and thyroxine. Exp Eye Res. 89: 854-862. books

Beazley KE, Nurminskaya M, Linsenmayer TF. 2009. Phosphorylation regulates the ferritoid-ferritin interaction and nuclear transport. J Cell Biochem. 107: 528-536. books

Cairns DM, Lee PG, Uchimura T, Seufert C, Kwon H, Zeng L. 2009. The role of muscle cells in regulating cartilage matrix production. J Orthop Res. 28: 529-536. Abstract in PubMed

DiMeo TA, Anderson K, Fen C, Padkhe P, Naber S, Perou C, Kuperwasser C. 2009. A novel lung metastasis signature links wnt signaling with cancer cell self-renewal and the epithelial-mesenchymal transition in basal-like breast cancer. Cancer Res. 69: 5364-5373. books 

Diskin S, Cao Z, Leffler H, Panjwani N. 2008. The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. Glycobiology 19: 29-37. books

Diskin S, Panjwani N. 2008. Carbohydrate-based recognition systems in primary open angle glaucoma.  Curr Org Chem. 12:  911-917.

Greenberg L,  Hatini V. 2009. Essential roles for lines in mediating leg and antennal proximodistal patterning and generating a stable Notch signaling interface at segment borders. Dev Biol. 330: 93–104.  books

Hewitt KJ, Shamis Y, Carlson MW, Aberdam E, Aberdam D, Garlick JA. 2009. Three-dimensional epithelial tissues generated from human embryonic stem cells. Tissue Eng Part A 15: 3417-3426. books

Myers JP, vom Saal FS, Akingbemi BT, Arizono K, Belcher S, Colborn T, Chahoud I, Crain DA, Farabollini F, Guillette LJ Jr, Hassold T, Ho SM, Hunt PA, Iguchi T, Jobling S, Kanno J, Laufer H, Marcus M, McLachlan JA, Nadal A, Oehlmann J, Olea N, Palanza P, Parmigiani S, Rubin BS, Schoenfelder G, Sonnenschein C, Soto AM, Talsness CE, Taylor JA, Vandenberg LN, Vandenbergh JG, Vogel S, Watson CS, Welshons WV, Zoeller RT. 2009. Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect. 117:309-315. books

Nurminskaya MV, Talbot CJ, Nurminsky DI, Beazley KE, Linsenmayer TF. 2009. Nuclear ferritin: a ferritoid-ferritin complex in corneal epithelial cells. Invest Ophthalmol Vis Sci. 50: 3655-3661. books

Rosenberg M, Yang F, Giovanni M, Mohn JL, Temburni MK, Jacob MH. 2008. Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex. Mol Cell Neurosci. 38: 138- 152. books  

Saravanan C, Liu FT, Gipson IK, Panjwani N. 2009. Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on α3β1 integrin. J Cell Sci. 122: 3684-3693. books

Saravanan C, Cao Z, Head SR, Panjwani N. 2009. Detection of differentially expressed wound-healing-related glycogenes in galectin-3-deficient mice. Invest Ophthalmol Vis Sci. 50: 5690-5696. books

Vandenberg LN, Maffini MV, Sonnenschein C, Rubin BS, Soto AM. 2009. Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption. Endocr Res. 30: 75-95. books

Wei L, McKeon F, Russo JW, Lemire J, Castellot J. 2009. Domain-and species-specific monoclonal antibodies recognize the Von Willebrand Factor-C domain of CCN5. J Cell Commun Signal. 3: 65-77. books

Apply to the Sackler School


The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development