CMDB Faculty

Program Faculty with Active Research Programs

Please note that faculty designated as MMCRI are based in Scarborough, ME. Thesis research under the mentorship of these faculty is conducted at Maine Medical Center Research Institute in Scarborough,ME.

Ira Herman, PhD, Program Director - Mechanics of motility, angiogenesis and wound healing: Therapeutics for regenerative medicine Send an e-mail  PI Profile

William Bachovchin, PhD - Structure-based drug design  Send an e-mail PI Profile

James Baleja, PhD - Molecular recognition, structure-based drug design, NMR-based protein structure determination  Send an e-mail  PI Profile

Thomas Biederer, PhD - Molecular mechanisms of synapse formation Send an e-mail  PI Profile

Lauren Black, III, PhD - Cardiovascular tissue engineering Send an e-mail  PI Profile

Alex Andrew Bohm, PhD - RNA processing complexes; replication initiation  Send an e-mail  PI Profile

Peter Brooks, PhD (MMCRI) - Extracellular matrix and inflammation; angiogenesis and tumor progression Send an e-mail  PI Profile

Peter Bullock, PhD - Structure-based studies of DNA replication initiation; viral inhibitor design using chemical genetics  Send an e-mail  PI Profile

Jake Jinkun Chen, DDS, PhD - Cell and molecular biology of bone Send an e-mail  PI Profile 

Athar Chishti, PhD - Understanding the cytoskeleton in health and disease Send an e-mail  PI Profile

Brent Cochran, PhD - Glioblastoma stem cells and molecular mechanisms of brain cancer Send an e-mail  PI Profile

Lidija Covic, PhD - Protease activated receptors and cancer metastasis  Send an e-mail  PI Profile    

Daniel Cox, PhD - Molecular mechanisms of BKCa channel function  Send an e-mail  PI Profile

Alexei Degterev, PhD - Mechanisms of cell death using small molecule and drug probes  Send an e-mail  PI Profile

Chris Dulla, PhD - Spatiotemporal control of neurotransmitter transients Send an e-mail  PI Profile

Larry Feig, PhD - Ras and Ral GTPase signaling in cancer, and learning and memory  Send an e-mail  PI Profile

Michael Forgac, PhD - Mechanism of regulation of vacuolar acidification  Send an e-mail  PI Profile

Robert Friesel, PhD (MMCRI) - Angiogenesis, tissue remodeling and development Send an e-mail  PI Profile

Marta Gaglia, PhD - Virus - host interaction in KSHV infection  Send an e-mail  PI Profile

Jonas Galper, MD, PhD - Sterol regulation of cardiovascular disease Send an e-mail  PI Profile

Jonathan Garlick, DDS, PhD - Cell-cell interaction in squamous cell carcinoma; stem cells and tissue regeneration Send an e-mail  PI Profile

Thomas Gridley, PhD (MMCRI) - Notch signaling in development and disease Send an e-mail  PI Profile

Pedram Hamrah, MD - Antigen presentation mechanisms  Send an e-mail  PI Profile

Victor Hatini, PhD - Genetic approaches to patterning and organ development Send an e-mail  PI Profile

Ekaterina Heldwein, PhD - Structural and mechanistic studies of herpesvirus entry into host cells  Send an e-mail  PI Profile

Philip Hinds, PhD - Retinoblastoma pathway in differentiation, senescence, and cancer  Send an e-mail  PI Profile

Guo-fu Hu, PhD - Angiogenesis in cancer and neurodegeneration Send an e-mail  PI Profile

Gordon Huggins, MD - Molecular genetic mechanisms of cardiovascular development and disease Send an e-mail  PI Profile

John Iacomini, PhD - Immunological responses in transplantation and tissue injury Send an e-mail  PI Profile

Michele Jacob, PhD - Molecular mechanisms dirrecting synapse assembly and plasticity Send an e-mail  PI Profile

Iris Jaffe, MD, PhD - Aldosterone and the mineralocorticoid receptor in vascular function and disease Send an e-mail  PI Profile

Daniel Jay, PhD - Mechanisms of cancer metastasis Send an e-mail  PI Profile

Peter Juo, PhD - Localization and regulation of synaptic proteins Send an e-mail  PI Profile

David Kaplan, PhD - Tissue engineering and stem cells Send an e-mail  PI Profile

Dong Kong, PhD -  Synaptic plasticity and circuitry in neuron-metabolism  Send an e-mail  PI Profile

Joshua Krtizer, PhD -  Peptides and peptidomimetics targeting biological processes  Send an e-mail  PI Profile

James Kubilus, PhD - Signaling in cornea development  Send an e-mail  PI Profile

Athan Kuliopulos, MD, PhD - Protease activated receptors in vascular biology and cancer  Send an e-mail  PI Profile

Rajendra Kumar-Singh, PhD - Gene therapy for inherited retinal disorders Send an e-mail  PI Profile

Charlotte Kuperwasser, PhD - Molecular mechanisms of breast cancer development Send an e-mail  PI Profile  

Cynthia Leveille-Webster, DVM - Role of cAMP in hepatocyte survival Send an e-mail   PI Profile

Lucy Liaw, PhD (MMCRI) -Blood vessel development and repair Send an e-mail  PI Profile

Volkhard Lindner, MD, PhD (MMCRI) - Genes associated with vascular injury and repair Send an e-mail  PI Profile

Claire Moore, PhD - Mechanism and regulation of mRNA polyadenylation  Send an e-mail  PI Profile

Karl Munger, PhD - HPV-mediated oncogenesis  Send an e-mail  PI Profile

James Munro, PhD - Molecular mechanisms of viral entry  Send an e-mail  PI Profile

Leif Oxburgh, DVM, PhD (MMCRI) - BMP and regulation of kidney development Send an e-mail  PI Profile

Noorjahan Panjwani, PhD - Corneal disease mechanisms Send an e-mail  PI Profile

Ilka Pinz, PhD (MMCRI) - Lipotoxicity and heart disease Send an e-mail  PI Profile

Igor Prudovsky, PhD (MMCRI) - Molecular events associated with protein release Send an e-mail  PI Profile

Malavika Raman, PhD - Mechanisms of protein homeostasis  Send an e-mail PI Profile

Maribel Rios, PhD - Obesity and mood disorders; neurodegeneration Send an e-mail  PI Profile

Rebecca Scheck, PhD - Chemical approaches to posttranslational networks   Send an e-mail PI Profile

Gavin Schnitzler, PhD - Chromatin remodeling and gene expression  Send an e-mail   PI Profile

James Schwob, MD, PhD - Olfactory system development and regeneration Send an e-mail PI Profile

Ana Soto, MD - Control of cell proliferation Send an e-mail  PI Profile

Allen Taylor, PhD - Aging and protein quality control, specifically in age-related eye disease and diet  Send an e-mail  PI Profile

Theoharis Theoharides, MD, PhD - Mast cell responses and inflammation  Send an e-mail  PI Profile

Philip Tsichlis, MD - Molecular mechanisms of leukemogenesis and gene discovery  Send an e-mail   PI Profile

Saul Tzipori, BVSc, PhD - Enteric infections and host responses Send an e-mail

Calvin Vary, PhD (MMCRI) -TGFβ in vascular development and disease Send an e-mail  PI Profile

David Walt, PhD - Detection of single molecules using optical fiber arrays  Send an e-mail  PI Profile

Don Wojchowski, PhD (MMCRI) - Regulation of erythropoiesis and anemia development Send an e-mail  PI Profile

Qiaobing Xu, PhD - Synthetic materials for the delivery of therapeutic biomacromolecules Send an e-mail  PI Profile

Pamela Yelick, PhD - Genetic analysis of craniofacial and tooth development Send an e-mail   PI Profile

Yongjie Yang, PhD - Astrocyte function and neurological disorders Send an e-mail  PI Profile

Amy Yee, PhD - Breast cancer, stem cells and transcriptional regulation  Send an e-mail  PI Profile 

Li Zeng, PhD - Cartilage development and regeneration Send an e-mail  PI Profile

Program Faculty Participating in Teaching

Debbie Beasley, PhD - Innate immunity and vascular disease Send an e-mail  PI Profile

John Castellot, PhD - Mechanisms of smooth muscle proliferation Send an e-mail  PI Profile

David Damassa, PhD - Steroid hormone signaling networks Send an e-mail  PI Profile

Christiane Dammann, MD - Fetal lung development Send an e-mail  PI Profile

Al-Walid El-Bermani, PhD - Mechanisms involved in innervation of the lung Send an e-mail  PI Profile

Mark Ewen, PhD - Mammary gland development and tumorigenesis  Send an e-mail  PI Profile

Eric Frank, PhD - Molecular mechanisms mediating synaptic connections between neurons Send an e-mail  PI Profile

Alvar Gustafson, PhD - Male reproductive physiology Send an e-mail  PI Profile

Douglas Jefferson, PhD - CF and ADPKD-associated hepatobiliary disease Send an e-mail   PI Profile

Giannoula Klement, MD - Platelet-facilitated cell-cell communication in cancer  Send an e-mail  PI Profile

Janis Lem, PhD - Retinal degeneration mechanisms and phototransduction Send an e-mail  PI Profile

Thomas Linsenmayer, PhD - Corneal development and innervation; oxidative damage protective mechanisms Send an e-mail  PI Profile

Laura Liscum, PhD - Intracellular cholesterol transport and metabolism Send an e-mail  PI Profile

Jeffrey Marchant, PhD - Tissue engineering and cornea replacement Send an e-mail PI Profile

Karina Meiri, PhD - Regulation of neurogenesis and neuronal plasticity  Send an e-mail  PI Profile

Heber Nielsen, MD - Normal and abnormal regulation of fetal lung development Send an e-mail  PI Profile

K Eric Paulson, PhD - ROS signaling and cancer  Send an e-mail  PI Profile

Beverly Rubin, PhD - Effects of perinatal xenoestrogen on body weight and fetal development Send an e-mail  PI Profile

G Gary Sahagian, PhD - Lysosomal trafficking and function in cancer; organ-selective metastasis in breast cancer Send an e-mail  PI Profile

Brian Schaffhausen, PhD - Mechanism of neoplastic transformation  Send an e-mail  PI Profile

Gail Sonenshein, PhD - Signaling in breast cancer  Send an e-mail  PI Profile

Carlos Sonnenschein, MD - Proliferation of estrogen-dependent cells Send an e-mail  PI Profile

Apply to the Sackler School

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The priority application deadlines are as follows:

December 1: Basic Science Division PhD Programs

February 15: Building Diversity in Biomedical Sciences

March 31: Post-Baccalaureate Research Program

May 1: Clinical & Translational Science, MS in Pharmacology & Drug Development

June 15: Online Certificate in Fundamentals of Clinical Care Research