Claire Metrick


Claire Metrick
BS, Biomedical Engineering
Boston University
Boston, MA 
Biochemistry PhD Student
Katya Heldwein, PhD, Adviser





Herpesvirus egress is a process by which the newly-replicated viral genetic material is packaged and released from the host cell as infectious particles. This process consists of budding events from the nucleus through the trans-golgi network that are regulated by many viral proteins including tegument proteins UL11, UL16, and UL21. Although these proteins are highly conserved among herpesviruses, their exact functions are still unclear. I aim to determine the structures of these proteins alone and in complex in order to elucidate how they interact and work to regulate cytoplasmic budding processes during viral egress and ultimately affect cell-to-cell spread of the disease.

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    February 15: Building Diversity in Biomedical Sciences

    March 31: Post-Baccalaureate Research Program

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